Bioactive Products
| A unique collection of 165 natural compounds used for Hepatoprotective research and Hepatoprotective drug screening. | ||
| Catalog No: | B36 | Hepatoprotective Compound Library Screening Details |
| Size: | 1mg/well * 165 Compounds 2mg/well * 165 Compounds | |
| Cat. No. | Information |
| CFN92766 | Loureirin A Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling. Loureirin A activates Wnt/-catenin pathway and promotes hair follicle stem cells (FSCs)-seeded tissue-engineered skin to repair skin wound.The molecular mechanism of Loureirin A and Wnt signaling pathway mediated anti- hepatic fibrosis and anti- angiogenesis may involve down- regulation the expression of Frizzled- 4,inhibiting the synthesis and secretion of α- SMA,TGF- β1and the proliferation of HSCs. |
| CFN92788 | Mulberrofuran G Mulberrofuran G shows moderate activity, inhibits hepatitis B virus (HBV) DNA replication with the IC(50) value of 3.99 μM. |
| CFN92802 | 14-Deoxyandrographolide 14-Deoxyandrographolide has hepatoprotective activity, mediates activation of adenylate cyclase-cAMP signaling leading to up-regulation of cNOS, may provide a promising approach in the prevention of liver diseases during chronic alcoholism. It desensitizes hepatocytes to TNF-alpha-mediated apoptosis through the release of TNFRSF1A. |
| CFN90566 | 7-Methoxycoumarin 7-Methoxycoumarin, also known as Herniarin, has potent antioxidant, hepatoprotective, and antitumor effects. 7-Methoxycoumarin has a weak estrogenic activity in vitro and in vivo, it could be beneficial with regard to vagina dryness as it showed a tissue specific effect without exposing the uterus to a potential tumorigenic growth. |
| CFN90583 | Tetrahydrocurcumin Tetrahydrocurcumin can inhibit tumor angiogenesis, treat human breast cancer,and be a promising candidate for the prevention of CIPN by chemotherapeutic agents.Tetrahydrocurcumin exhibits protective effects against cisplatin-induced oxidative renal damage in rats by inhibiting cyclooxygenase-2 and caspase-3 activation; it has a protective effect over arsenic induced toxicity in rat. |
