Bioactive Products
| A unique collection of 267 Inhibitor natural compounds | ||
| Catalog No: | Bb221 | Inhibitors Compound Library Screening Details |
| Size: | 1mg/well * 267 Compounds 2mg/well * 267 Compounds | |
| Cat. No. | Information |
| CFN90928 | Cyclopamine Cyclopamine is a Hedgehog (Hh) pathway antagonist with an IC50 of 46 nM in the Hh cell assay, it can increase levels of p27, and decreases both expression of IGF-II and activation of Akt in PC-3 prostate cancer cells. Cyclopamine as a novel, potent inhibitor of human breast cancer proliferation and estrogen responsiveness that could potentially be developed into a promising therapeutic agent for the treatment of breast cancer. Cyclopamine also can suppress the growth of leukemia and lymphoma cells. |
| CFN93051 | Kushenol F Kushenol F is a tyrosinase inhibitor, it shows significant inhibitory effects on monoamine oxidase ( in a dose-dependent manner with IC50 values of 69.9 microM). Kushenol F preferentially inhibits the MAO-B activity than MAO-A activity with the IC50 values of 63.1 and 103.7 microM, respectively. |
| CFN90991 | Beta-Elemonic acid Beta-Elemonic acid exhibits anti-inflammatory, and anti-cancer effects, it inhibits proliferation by inducing hypoploid cells and cell apoptosis, the anticancer effects of beta-Elemonic acid are related to the MAPK signaling pathway, ROS activation and glutathione depletion in human A549 lung cancer cells. Beta-Elemonic acid exhibits prolyl endopeptidase inhibitory activities. |
| CFN93187 | Luteolin-3-O-beta-D-glucuronide Luteolin 3'-O-beta-D-glucuronide is active in the inhibition of nitrite production in macrophages. |
| CFN90911 | Desoxyrhaponticin Desoxyrhaponticin is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes. Desoxyrhaponticin could be considered as a promising fatty acid synthase(FAS) inhibitor, it could inhibit intracellular FAS activity and downregulate FAS expression in human breast cancer MCF-7 cells. |
