Ajuga ciliata Bunge, Herbs perennial. Stems erect, 25-40 cm tall, purplish red or greenish red. Petiole 1 cm or more, sometimes purple-red, amplexicaul, gray pilose or ciliate only on margin; leaf blade ovate-elliptic to narrowly elliptic.
Three new (1-3) and three known (4-6) neo-clerodane diterpenes have been isolated from the whole plants of Ajuga ciliata Bunge. The structures of the new compounds were elucidated as (12S)-1β,6α,19-triacetoxy-18-chloro-4α,12-dihydroxy-neo-clerod-13-en-15,16-olide (1), (12S,2'S)-12,19-diacetoxy-18-chloro-4α,6α-dihydroxy-1β-(2-methylbutanoyloxy)-neo-clerod-13-en-15,16-olide (2), and (12S)-6α,18,19-triacetoxy-4α,12-dihydroxy-1β-tigloyloxy-neo-clerod-13-en-15,16-olide (3), on the basis of spectroscopic data analysis. All the diterpenes were evaluated for the neuroprotective effects against MPP(+)-induced neuronal cell death in dopaminergic neuroblastoma SH-SY5Y cells and compounds 2-5 exhibited moderate neuroprotective effects.
Catalog | Product Name | CAS Number | Manual |
---|---|---|---|
CFN97439 | Dihydroajugapitin | 87480-84-0 | n/a |
CFN92751 | Ajugamarin F4 | 122587-84-2 | n/a |
CFN92752 | Ajugacumbin A | 124961-66-6 | |
CFN92753 | Ajugamarin H1 | 122616-88-0 | n/a |
CFN92754 | Ajugamarin G1 | 122587-83-1 | n/a |
CFN92755 | Ajuganipponin A | 936323-13-6 | n/a |
CFN92756 | Ajugatakasin A | 197723-20-9 | n/a |
CFN92757 | Ajugamarin L2 (Ajugacumbin B) | 124961-67-7 | n/a |
CFN92758 | Ajugapantin A | 121449-67-0 | n/a |
CFN92759 | Ajugamarin chlorohydrin | 85447-27-4 | n/a |
CFN92760 | Ajugalide D | 853247-65-1 | n/a |
CFN90616 | Ajugasterone C | 23044-80-6 | |
CFN91959 | Ajugalide C | 853247-64-0 | n/a |
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