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Screening Libraries
Schisandra chinensis (Turcz.) Baill.
A unique collection of 36 Schisandra chinensis (Turcz.) Baill. for high throughput screening (HTS), high content screening (HCS) and New drug research
Cat. Size Price Stock
P201581mg/well * 36 CompoundsInquiry In stock
Contact Us
P20158100uL/well (10mM solution) * 36 CompoundsInquiry In stock
*You can select compounds, quantities, format (dry/solid or DMSO) and plate map to meet your specific requirement.
Contact Us
E-mail manager@chemfaces.com
Tel (0086)-27-8423-7683
Shelf Life (0086)-27-84254680
ManufacturerWuhan ChemFaces Biochemical Co., Ltd.
Package & Storage
Container 96 Well Format Sample
Storage Protected from air and light, refrigerate or freeze(2-8 °)
Shelf Life 24 months (2-8 °)
Intended UseFor research use only. Not for human use. Not sell to patients
Description & Advantages
1. The products in the ChemFaces screening libraries are all from plants.
2. The biological activities or pharmacological activities of all the ChemFaces products are derived from the databases of all over the world the latest literatures, you can according to the product manuals on our website to access the relevant literatures, hope that our informations can give some inspirations and help to your research.
3.The collections of unique natural products, which include antioxidants, anti-inflammatory, antibacterial, anticancer, and ect. Can be used for high throughput screening (HTS) and high content screening (HCS), is to help you carry out new drug screening, the emergence of new indications and other professional tools.
4.Structurally diverse, medicinally active, and cell permeable, NMR and HPLC validated to ensure high purity.
5. ChemFaces offers customized bioactive screening libraries , whereby you choose the specific compounds you want in the library, the quantities, plate map, concentration, and format (dry/solid or DMSO solution).
Natural Products
Catalog No. Information
CFN99925 Schisantherin A

Schisantherin A exhibits anti-tussive, sedative, anti-inflammatory, antioxidant, anti-osteoporotic, neuroprotective, cognition enhancing, and cardioprotective activities. Schisantherin A can significantly attenuate Aβ1-42-induced learning and memory impairment and noticeably improve the histopathological changes in the hippocampus. Schisantherin A exhibits neuroprotection against 1-methyl-4-phenylpyridinium ion (MPP(+)) through the regulation of two distinct pathways including increasing CREB-mediated Bcl-2 expression and activating PI3K/Akt survival signaling.
CFN99924 Schisantherin B

Schisantherin B may protect against cognitive deficits and neurodegeneration induced by Aβ1-42 in mice by regulating the glutamate transporter type 1 (GLT-1) restoration as well as the capacity of Glycogen synthase kinase3β(GSK3β), it also shows good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis.
CFN99923 Schizandrin B

Schisandrin B, a kind of ATR and P-gp inhibitor with high safety, has been shown to produce antioxidant effect on rodent liver and heart. It also has anti-photoaging, and presents promising activities for future development of protective agents against CisPt nephrotoxicity. Combination of schizandrin B and paclitaxel(PTX) can enhance anti-tumor effects and relieve side effects of PTX on rats with mammary carcinoma.
CFN99922 Schizandrin A

Schisandrin A , an agonist of the adiponectin receptor 2 (AdipoR2) with the IC50 value of 3.5 μM, has neuroprotective, anti-inflammatory, liver-protective, antitumor, and antioxidant activities. It alleviated microglia-mediated neuroinflammation injury through inhibiting the TRAF6-IKKβ-NF-κB and Jak2-Stat3 signaling pathways. It inhibited CYP3A activity with an IC50 of 6.60 μM and Ki of 5.83 μM, respectively.
CFN99708 Schizandrin C

Schizandrin C isolated from Schisandra chinensis could be used as a natural anti-neuroinflammatory agent, inducing phase II detoxifying/antioxidant enzymes via cAMP/PKA/CREB and Nrf-2 signaling.
CFN99012 Schisandrol A

Schisandrol A may be a new promising treatment for neurotoxicity, erectile dysfunction and cardiovascular disease.It can inhibit the activities of Pgp,Beta Amyloid,CYP3A4,cGMP,and NOS, the IC(50) value of CYP3A4 is 32.02 microM.
CFN98990 Gomisin A

Gomisin A has anti-inflammatory, antihypertensive, neuroprotective, and anti-proliferation properties, it induces marked protective effects against hepatic and renal injury induced by CCl(4) exposure through differential regulation of the MAPK signal transduction pathway. Gomisin A inhibits COX-2, iNOS, IL-6, TNF-α and NO through the down-regulation of RIP2 and NF-κB activation.
CFN98539 Anwulignan

Anwuligan has antimicrobial and anticariogenic activity against Streptococcus mutans and other streptococcus species. It also shows antioxidant, free radical scavenging, and neuroprotective activities. (+)-Anwulignan has inhibitory effects on platelets aggregation induced by adenosine diphosphate (ADP) and platelet activating factor(PAF) in vitro.
CFN90364 Schisanhenol

Schisanhenol has antioxidative effect on human LDL oxidation, may be through scavenging free radicals; it also has anti-apoptosis effect on BACSs, may be related to its inhibition of ROS generation. Schisanhenol can protect against adriamycin induced heart mitochondrial toxicity.
CFN90125 Gomisin N

Gomisin N has anti-oxdiant, anti-inflammatory, anti-cancer and anti-hepatitis activities; it produces beneficial sedative and hypnotic bioactivity, which may be mediated by the modification of the serotonergic and GABAergic system. Gomisin N can enhance TNF-α-induced apoptosis by suppressing of NF-κB and EGFR signaling pathways, and potentiate TRAIL-induced apoptosis through ROS-mediated up-regulation of death receptors 4 and 5.