1,3-Diacetylvilasinin | CAS:78012-28-9

1,3-Diacetylvilasinin

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Description:

1,3-Diacetylvilasinin shows marginal cytotoxicities against certain human tumor cell lines. It also shows antifeeding activity towards insects.

In vitro:

J Nat Prod. 1998 Jan;61(1):64-70.

New bioactive triterpenoids from Melia volkensii.[Pubmed: 9461654]

METHODS AND RESULTS:
Bioactivity-directed fractionation of the root bark of Melia volkensii resulted in the isolation of two new natural products, meliavolkinin (1) and melianin C (3), together with two known compounds, 1,3-Diacetylvilasinin (2) and melianin B (4). Jones oxidation of 4 gave compounds 3, 23,24-diketomelianin B (5), and 16,23,24-triketomelianin B (6). The structures of the new compounds were elucidated by spectral and chemical data.
CONCLUSIONS:
Compounds 1-6 all showed marginal cytotoxicities against certain human tumor cell lines, while 5 showed selective cytotoxicities for the human prostate (PC-3) and pancreatic (PACA-2) cell lines with potencies comparable to those of adriamycin.

1,3-Diacetylvilasinin Description

Source:	The barks of Azadirachta indica
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	1,3-Diacetylvilasinin
Price:
CAS No.:	78012-28-9
Catalog No.:	CFN97682
Molecular Formula:	C₃₀H₄₀O₇
Molecular Weight:	512.64 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	Powder
Source:	The barks of Azadirachta indica
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Cytotoxic Compound Library Antifeedant Compound Library Triterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.9507 mL	9.7534 mL	19.5069 mL	39.0137 mL	48.7672 mL
5 mM	0.3901 mL	1.9507 mL	3.9014 mL	7.8027 mL	9.7534 mL
10 mM	0.1951 mL	0.9753 mL	1.9507 mL	3.9014 mL	4.8767 mL
50 mM	0.039 mL	0.1951 mL	0.3901 mL	0.7803 mL	0.9753 mL
100 mM	0.0195 mL	0.0975 mL	0.1951 mL	0.3901 mL	0.4877 mL

CFN96441	Walsuralactam A	1370556-82-3	437.53	C₂₆H₃₁NO₅
CFN99368	Cedrelone	1254-85-9	422.5	C₂₆H₃₀O₅
CFN98345	11beta-Hydroxycedrelone	283174-18-5	438.5	C₂₆H₃₀O₆
CFN97517	Walsuronoid B	942582-15-2	438.5	C₂₆H₃₀O₆
CFN97682	1,3-Diacetylvilasinin	78012-28-9	512.64	C₃₀H₄₀O₇
CFN99908	Toosendanin	58812-37-6	574.62	C₃₀H₃₈O₁₁