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10-Methoxygambogenic acid
10-Methoxygambogenic acid
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 10-Methoxygambogenic acid
Price: $318 / 10mg
CAS No.: 2095102-72-8
Catalog No.: CFN95450
Molecular Formula: C39H50O9
Molecular Weight: 662.8 g/mol
Purity: >95%
Type of Compound: Miscellaneous
Physical Desc.: Powder
Source: The herbs of Garcinia hanburyi Hook. f.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $251.2 / In-stock
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 10-Methoxygambogenic acid is highly cytotoxic to HL-60, SMMC-7721 and BGC-83 cells.
In vitro:
J Asian Nat Prod Res. Sep-Dec 2007;9(6-8):735-741.
Five novel prenylated xanthones from Resina Garciniae[Pubmed: 17994391]
Fourteen prenylated xanthone derivatives were isolated from gamboge, the dry latex of Garcinia hanburyi, and their structures were elucidated by a detailed spectroscopic analysis. Five of them, isogambogenic acid (1), desoxymorellinin (2), 10-Methoxygambogenic acid (3), 10-methoxygambogic acid (4) and 10-ethoxy gambogic acid (5), are new compounds. All of them showed potent cytotoxicity against HL-60, SMMC-7721 and BGC-83 cells.
10-Methoxygambogenic acid Description
Source: The herbs of Garcinia hanburyi Hook. f.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.5088 mL 7.5438 mL 15.0875 mL 30.175 mL 37.7188 mL
5 mM 0.3018 mL 1.5088 mL 3.0175 mL 6.035 mL 7.5438 mL
10 mM 0.1509 mL 0.7544 mL 1.5088 mL 3.0175 mL 3.7719 mL
50 mM 0.0302 mL 0.1509 mL 0.3018 mL 0.6035 mL 0.7544 mL
100 mM 0.0151 mL 0.0754 mL 0.1509 mL 0.3018 mL 0.3772 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Asian Nat Prod Res. Sep-Dec 2007;9(6-8):735-741.
Five novel prenylated xanthones from Resina Garciniae[Pubmed: 17994391]
Fourteen prenylated xanthone derivatives were isolated from gamboge, the dry latex of Garcinia hanburyi, and their structures were elucidated by a detailed spectroscopic analysis. Five of them, isogambogenic acid (1), desoxymorellinin (2), 10-Methoxygambogenic acid (3), 10-methoxygambogic acid (4) and 10-ethoxy gambogic acid (5), are new compounds. All of them showed potent cytotoxicity against HL-60, SMMC-7721 and BGC-83 cells.
CFN90172Gambogic acid2752-65-0628.75C38H44O8
CFN90175Neogambogic acid93772-31-7646.77C38H46O9
CFN95440Isogambogic acid149655-52-7628.8C38H44O8
CFN92089Gambogin173792-67-1598.8C38H46O6
CFN92098Epigambogic acid887606-04-4628.8C38H44O8
CFN9210130-Hydroxygambogic acid881027-36-7644.8C38H44O9
CFN920999R-10alpha-Hydroxyepigambogic acid1097882-33-1646.8C38H46O9
CFN9210010alpha-Hydroxyepigambogic acid1164201-85-7646.8C38H46O9
CFN95439Gambogoic acid A887923-49-1660.8C39H48O9
CFN92957Gambogoic acid B887923-50-4674.82C40H50O9
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