Science | Nature | Cell | View More
Natural Products
2,3',4,6-Tetrahydroxybenzophenone
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 2,3',4,6-Tetrahydroxybenzophenone
Price:
CAS No.: 26271-33-0
Catalog No.: CFN98302
Molecular Formula: C13H10O5
Molecular Weight: 246.2 g/mol
Purity: >=98%
Type of Compound: Xanthones
Physical Desc.: Yellow powder
Source: The herbs of Garcinia cowa
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Siksha O Anusandhan University (India)
  • Universidade Federal de Pernamb... (Brazil)
  • University of Maryland (USA)
  • Helmholtz Zentrum München (Germany)
  • Melbourne University (Australia)
  • University of Perugia (Italy)
  • Massachusetts General Hospital (USA)
  • Universit?t Basel (Switzerland)
  • University of Canterbury (New Zealand)
  • University of Medicine and Phar... (Romania)
  • National Hellenic Research Foun... (Greece)
  • More...
Package
Featured Products
Harpagoside

Catalog No: CFN98147
CAS No: 19210-12-9
Price: $70/20mg
Acteoside

Catalog No: CFN97048
CAS No: 61276-17-3
Price: $60/20mg
Aristolochic acid A

Catalog No: CFN99505
CAS No: 313-67-7
Price: $80/20mg
Irisflorentin

Catalog No: CFN99788
CAS No: 41743-73-1
Price: $40/20mg
Alpha-caryophyllene

Catalog No: CFN93582
CAS No: 6753-98-6
Price: $40/20mg
Neochamaejasmine A

Catalog No: CFN92151
CAS No: 90411-13-5
Price: $418/5mg
Genipin

Catalog No: CFN99142
CAS No: 6902-77-8
Price: $40/20mg
Hyperoside

Catalog No: CFN98754
CAS No: 482-36-0
Price: $50/20mg
Rosavin

Catalog No: CFN99179
CAS No: 84954-92-7
Price: $68/20mg
Afrormosine

Catalog No: CFN92347
CAS No: 550-79-8
Price: $ / mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 2,3',4,6-Tetrahydroxybenzophenone possesses significant antioxidant activity.
Targets: P450 (e.g. CYP17)
In vitro:
Bioorg Chem. 2014 Jun;54:60-7.
Cytotoxic benzophenone and triterpene from Garcinia hombroniana.[Pubmed: 24813683]

METHODS AND RESULTS:
2,3',4,5'-tetrahydroxy-6-methoxybenzophenone(1), 2,3',4,4'-tetrahydroxy-6-methoxybenzophenone (2), 2,3',4,6-Tetrahydroxybenzophenone (3), 1,3,6,7-tetrahydroxyxanthone (4), 3,3',4',5,7-pentahydroxyflavone (5),3,3',5,5',7-pentahydroxyflavanone (6), 3,3',4',5,5',7-hexahydroxyflavone (7), 4',5,7-trihydroxyflavanone-7-rutinoside (8), 18(13→17)-abeo-3β-acetoxy-9α,13β-lanost-24E-en-26-oic acid (9), garcihombronane B (10), garcihombronane D (11), friedelan-3-one (12), lupeol (13), stigmasterol (14) and stigmasterol glucoside (15).
CONCLUSIONS:
In the in vitro cytotoxicity against MCF-7, DBTRG, U2OS and PC-3 cell lines, compounds 1 and 9 displayed good cytotoxic effects against DBTRG cancer cell lines. Compounds 1-8 were also found to possess significant antioxidant activities. Owing to these properties, this study can be further extended to explore more significant bioactive components of this plant.
2,3',4,6-Tetrahydroxybenzophenone Description
Source: The herbs of Garcinia cowa
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Foliachinenoside C

Catalog No: CFN95361
CAS No: 1041180-87-3
Price: $368/5mg
(R)-5,3'-Dimethyl hesperidin

Catalog No: CFN95310
CAS No: N/A
Price: $318/5mg
9-Hydroxy-O-senecioyl-8,9-dihydroo...

Catalog No: CFN95274
CAS No: 31456-63-0
Price: $318/5mg
3',5-Dihydroxy-4',6,7-trimethoxyfl...

Catalog No: CFN95316
CAS No: 90850-99-0
Price: $318/5mg
Methyl lucidenate C

Catalog No: CFN95541
CAS No: N/A
Price: $413/5mg
Yakuchinone A

Catalog No: CFN95555
CAS No: 78954-23-1
Price: $318/10mg
Isochlorogenic acid C 4'-O-glucosi...

Catalog No: CFN95405
CAS No: N/A
Price: $413/5mg
3beta-Hydroxyurs-12,18-dien-28-oic...

Catalog No: CFN95461
CAS No: 434942-42-4
Price: $318/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.0617 mL 20.3087 mL 40.6174 mL 81.2348 mL 101.5435 mL
5 mM 0.8123 mL 4.0617 mL 8.1235 mL 16.247 mL 20.3087 mL
10 mM 0.4062 mL 2.0309 mL 4.0617 mL 8.1235 mL 10.1543 mL
50 mM 0.0812 mL 0.4062 mL 0.8123 mL 1.6247 mL 2.0309 mL
100 mM 0.0406 mL 0.2031 mL 0.4062 mL 0.8123 mL 1.0154 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
FEBS Lett. 1997 Dec 29;420(2-3):143-6.
Alternative pathways of xanthone biosynthesis in cell cultures of Hypericum androsaemum L.[Pubmed: 9459298 ]

METHODS AND RESULTS:
The stepwise condensation of benzoyl-CoA with three molecules of malonyl-CoA, catalyzed by benzophenone synthase, yields 2,4,6-trihydroxybenzophenone. This intermediate is subsequently converted by benzophenone 3'-hydroxylase, a cytochrome P450 monooxygenase. These biosynthetic steps, leading to the formation of 2,3',4,6-Tetrahydroxybenzophenone, represent an alternative pathway to that recently proposed for cell cultures of Centaurium erythraea [Peters et al., Planta (1997) in press].
Harpagoside

Catalog No: CFN98147
CAS No: 19210-12-9
Price: $70/20mg
Acteoside

Catalog No: CFN97048
CAS No: 61276-17-3
Price: $60/20mg
Aristolochic acid A

Catalog No: CFN99505
CAS No: 313-67-7
Price: $80/20mg
Irisflorentin

Catalog No: CFN99788
CAS No: 41743-73-1
Price: $40/20mg
Alpha-caryophyllene

Catalog No: CFN93582
CAS No: 6753-98-6
Price: $40/20mg
Neochamaejasmine A

Catalog No: CFN92151
CAS No: 90411-13-5
Price: $418/5mg
Genipin

Catalog No: CFN99142
CAS No: 6902-77-8
Price: $40/20mg
Hyperoside

Catalog No: CFN98754
CAS No: 482-36-0
Price: $50/20mg
Rosavin

Catalog No: CFN99179
CAS No: 84954-92-7
Price: $68/20mg
Afrormosine

Catalog No: CFN92347
CAS No: 550-79-8
Price: $ / mg
Tags: buy 2,3',4,6-Tetrahydroxybenzophenone | 2,3',4,6-Tetrahydroxybenzophenone supplier | purchase 2,3',4,6-Tetrahydroxybenzophenone | 2,3',4,6-Tetrahydroxybenzophenone cost | 2,3',4,6-Tetrahydroxybenzophenone manufacturer | order 2,3',4,6-Tetrahydroxybenzophenone | 2,3',4,6-Tetrahydroxybenzophenone distributor