Structure Identification: |
Chem Pharm Bull (Tokyo). 2016;64(1):78-82. | Chromatographic Evaluation and Characterization of Components of Gentian Root Extract Used as Food Additives.[Pubmed: 26726749 ] | Gentian root extract is used as a bitter food additive in Japan.
METHODS AND RESULTS:
We investigated the constituents of this extract to acquire the chemical data needed for standardized specifications. Fourteen known compounds were isolated in addition to a mixture of gentisin and isogentisin: anofinic acid, 2-Methoxyanofinic acid, furan-2-carboxylic acid, 5-hydroxymethyl-2-furfural, 2,3-dihydroxybenzoic acid, isovitexin, gentiopicroside, loganic acid, sweroside, vanillic acid, gentisin 7-O-primeveroside, isogentisin 3-O-primeveroside, 6'-O-glucosylgentiopicroside, and swertiajaposide D. Moreover, a new compound, loganic acid 7-(2'-hydroxy-3'-O-β-D-glucopyranosyl)benzoate (1), was also isolated.
CONCLUSIONS:
HPLC was used to analyze gentiopicroside and amarogentin, defined as the main constituents of gentian root extract in the List of Existing Food Additives in Japan. |
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