Science | Nature | Cell | View More
Natural Products
4beta,12-dihydroxyguaian-6,10-diene
4beta,12-dihydroxyguaian-6,10-diene
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 4beta,12-dihydroxyguaian-6,10-diene
Price: $268 / 5mg
CAS No.: 461644-90-6
Catalog No.: CFN90947
Molecular Formula: C15H24O2
Molecular Weight: 236.34 g/mol
Purity: >=98%
Type of Compound: Monoterpenoids
Physical Desc.: Powder
Source: The rhizomes of Alisma orientale.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $152.6 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Fraunhofer-Institut für Moleku... (Germany)
  • Washington State University (USA)
  • University of Sao Paulo (Brazil)
  • University of Hull (United Kingdom)
  • Tohoku University (Japan)
  • Universidade Federal de Pernamb... (Brazil)
  • Instituto Politécnico de Bragan?a (Portugal)
  • Universiti Sains Malaysia (Malaysia)
  • Instituto de Investigaciones Ag... (Chile)
  • Kamphaengphet Rajabhat University (Thailand)
  • Nicolaus Copernicus Uniwersity (Poland)
  • More...
Package
Featured Products
Sinomenine

Catalog No: CFN99508
CAS No: 115-53-7
Price: $30/20mg
Oxypeucedanin

Catalog No: CFN90350
CAS No: 737-52-0
Price: $80/20mg
Gypenoside L

Catalog No: CFN91854
CAS No: 94987-09-4
Price: $268/5mg
Aurantiamide

Catalog No: CFN98984
CAS No: 58115-31-4
Price: $218/5mg
6',7'-Dihydroxybergamottin

Catalog No: CFN98307
CAS No: 264234-05-1
Price: $318/10mg
Euphol

Catalog No: CFN89516
CAS No: 514-47-6
Price: $158/10mg
Ginsenoside Ro

Catalog No: CFN99147
CAS No: 34367-04-9
Price: $100/20mg
Nerolidol

Catalog No: CFN98638
CAS No: 7212-44-4
Price: $30/20mg
Stigmasterol

Catalog No: CFN97326
CAS No: 83-48-7
Price: $30/20mg
Pyrogallol

Catalog No: CFN97443
CAS No: 87-66-1
Price: $30/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 4beta,12-dihydroxyguaian-6,10-diene is a natural product from Alisma orientale.
In vitro:
Arch Pharm Res. 2012 Nov;35(11):1919-26.
A new triterpenoid from Alisma orientale and their antibacterial effect.[Pubmed: 23212633 ]
A new triterpenoid, named alisol Q 23-acetate, as well as fourteen known terpenes, alisol B 23-acetate (2), alisol B (3), alismol (4), 10-O-methyl-alismoxide (5), alismoxide (6), 11-deoxyalisol C (7), 13β,17β-epoxyalisol B 23-acetate (8), 4beta,12-dihydroxyguaian-6,10-diene (9), alisol C 23-acetate (10), alisolide (11), 16β-methoxyalisol B monoacetate (12), alisol A (13), 16β-hydroxyalisol B 23-acetate (14), alisol A 24-acetate (15) were isolated from the rhizomes of Alisma orientale.
METHODS AND RESULTS:
The structures of compounds (1-15) were identified based on 1D and 2D NMR, including (1)H-(1)H COSY, HSQC, HMBC and NOESY spectroscopic analyses. Among these isolates, antibacterial effect of compounds 2, 3, 10, and 15, major constituents of A. orientale was examined. The MIC values of compounds 2, 10, and 15 were 5-10 βg/mL against eight antibiotic resistant strains, which were lower than those from the positive controls (MICs of chloramphenicol and ampicillin were 5-80 μg/mL).
CONCLUSIONS:
Therefore, compounds 2, 10 and 15 exhibited the potent antibacterial activity.
4beta,12-dihydroxyguaian-6,10-diene Description
Source: The rhizomes of Alisma orientale.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
cis-Mulberroside A

Catalog No: CFN95006
CAS No: 166734-06-1
Price: $418/10mg
Odontoside

Catalog No: CFN95530
CAS No: 20300-50-9
Price: $318/5mg
Planispine A

Catalog No: CFN95348
CAS No: 1202761-42-9
Price: $318/10mg
Tortoside B (Manglieside E)

Catalog No: CFN95390
CAS No: 190655-17-5
Price: $413/5mg
Methyl ganoderate D

Catalog No: CFN95581
CAS No: 97210-12-3
Price: $318/5mg
3'-Hydroxy-5,7,4',5'-Tetramethoxyf...

Catalog No: CFN95397
CAS No: 29976-51-0
Price: $318/5mg
Fragransin B1

Catalog No: CFN95443
CAS No: 112516-03-7
Price: $318/5mg
New compound 13

Catalog No: CFN95374
CAS No: N/A
Price: $318/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.2312 mL 21.156 mL 42.3119 mL 84.6238 mL 105.7798 mL
5 mM 0.8462 mL 4.2312 mL 8.4624 mL 16.9248 mL 21.156 mL
10 mM 0.4231 mL 2.1156 mL 4.2312 mL 8.4624 mL 10.578 mL
50 mM 0.0846 mL 0.4231 mL 0.8462 mL 1.6925 mL 2.1156 mL
100 mM 0.0423 mL 0.2116 mL 0.4231 mL 0.8462 mL 1.0578 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Sinomenine

Catalog No: CFN99508
CAS No: 115-53-7
Price: $30/20mg
Oxypeucedanin

Catalog No: CFN90350
CAS No: 737-52-0
Price: $80/20mg
Gypenoside L

Catalog No: CFN91854
CAS No: 94987-09-4
Price: $268/5mg
Aurantiamide

Catalog No: CFN98984
CAS No: 58115-31-4
Price: $218/5mg
6',7'-Dihydroxybergamottin

Catalog No: CFN98307
CAS No: 264234-05-1
Price: $318/10mg
Euphol

Catalog No: CFN89516
CAS No: 514-47-6
Price: $158/10mg
Ginsenoside Ro

Catalog No: CFN99147
CAS No: 34367-04-9
Price: $100/20mg
Nerolidol

Catalog No: CFN98638
CAS No: 7212-44-4
Price: $30/20mg
Stigmasterol

Catalog No: CFN97326
CAS No: 83-48-7
Price: $30/20mg
Pyrogallol

Catalog No: CFN97443
CAS No: 87-66-1
Price: $30/20mg
Tags: buy 4beta,12-dihydroxyguaian-6,10-diene | 4beta,12-dihydroxyguaian-6,10-diene supplier | purchase 4beta,12-dihydroxyguaian-6,10-diene | 4beta,12-dihydroxyguaian-6,10-diene cost | 4beta,12-dihydroxyguaian-6,10-diene manufacturer | order 4beta,12-dihydroxyguaian-6,10-diene | 4beta,12-dihydroxyguaian-6,10-diene distributor