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Antibiotic PF 1018
Antibiotic PF 1018
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Antibiotic PF 1018
Price:
CAS No.: 131256-42-3
Catalog No.: CFN00437
Molecular Formula: C28H35NO3
Molecular Weight: 433.59 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: From Sclerophoma pythiophila
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Antibiotic PF 1018 is an insecticidal agent.
Antibiotic PF 1018 Description
Source: From Sclerophoma pythiophila
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.3063 mL 11.5316 mL 23.0633 mL 46.1265 mL 57.6582 mL
5 mM 0.4613 mL 2.3063 mL 4.6127 mL 9.2253 mL 11.5316 mL
10 mM 0.2306 mL 1.1532 mL 2.3063 mL 4.6127 mL 5.7658 mL
50 mM 0.0461 mL 0.2306 mL 0.4613 mL 0.9225 mL 1.1532 mL
100 mM 0.0231 mL 0.1153 mL 0.2306 mL 0.4613 mL 0.5766 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
The Journal of Antibiotics, 1994, 47(5):571-80.
PF1018, a novel insecticidal compound produced by Humicola sp.[Pubmed: 8040055]

METHODS AND RESULTS:
A new insecticidal compound PF1018(Antibiotic PF 1018) was isolated from the culture broth of Humicola sp. It exhibited insecticidal activity against a wide range of critical pest species.
CONCLUSIONS:
The structure of PF1018 was determined to be (7aS)-2-((2E)-1-hydroxy-3-((1S,3aR,4R,5R,7aR)-3a,4,5,7 a-tetrahydro-1,3,5,7- tetramethyl-5,1-((3S)-(Z)-2,3-dimethylpropeno)-1H-inden-4-yl )-2- propenylidene)pyrrolizidine-1,3-dione, by NMR spectral analyses coupled with X-ray crystallographic analysis and chemical degradation study.
Lucidenic acid A

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CAS No: 95311-94-7
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Quercetin 3-O-glucoside-7-O-rhamno...

Catalog No: CFN90738
CAS No: 18016-58-5
Price: $388/10mg
Rubiadin 1-methyl ether

Catalog No: CFN97227
CAS No: 7460-43-7
Price: $268/10mg
Pinoresinol

Catalog No: CFN98775
CAS No: 487-36-5
Price: $188/20mg
Alisol B 23-acetate

Catalog No: CFN99753
CAS No: 26575-95-1
Price: $50/20mg
Panaxadiol

Catalog No: CFN99981
CAS No: 19666-76-3
Price: $40/20mg
Skullcapflavone II

Catalog No: CFN92216
CAS No: 55084-08-7
Price: $218/10mg
Brusatol

Catalog No: CFN93119
CAS No: 14907-98-3
Price: $168/20mg
Evodiamine

Catalog No: CFN99993
CAS No: 518-17-2
Price: $40/20mg
Gypenoside XLIX

Catalog No: CFN99717
CAS No: 94987-08-3
Price: $118/20mg
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