Asiaticoside B | CAS:125265-68-1 | Manufacturer ChemFaces

Asiaticoside B

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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $76.7 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Description:

Asiaticoside B has notable cytotoxicity against HepG2 and MCF-7 cancer cell lines.

In vitro:

J Nat Prod. 2006 Oct;69(10):1500-2.

Cytotoxic cycloartane triterpene saponins from Actaea asiatica.[Pubmed: 17067171 ]

METHODS AND RESULTS:
Three new 9,19-cycloartane triterpene glycosides, asiaticoside A (1), Asiaticoside B (2), and 25-O-ethylcimigenol-3-O-beta-D-xylopyranoside (3), together with cimiacemoside I (4), 25-O-acetylcimigenol-3-beta-O-D-xyloside (5), and 25-anhydrocimigenol-beta-O-D-xyloside (6) were isolated from the roots/rhizomes extract of Actaea asiatica, and their structures were established by spectroscopic methods (IR, HRESIMS, and NMR).
CONCLUSIONS:
Compounds 1-3, 5, and 6 had notable cytotoxicity against HepG2 and MCF-7 cancer cell lines.

Asiaticoside B Description

Source:	The herbs of Centella asiatica (L.) Urban
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Pharmazie. 2003 Jun;58(6):381-4.

An improved HPLC method for quantitative determination of six triterpenes in Centella asiatica extracts and commercial products.[Pubmed: 12856998]

METHODS AND RESULTS:
An improved HPLC qualitative and quantitative method of six triterpenes (asiaticoside, madecassoside, asiatic acid, madecassic acid, terminolic acid, and Asiaticoside B) in Centella asiatica (raw plant material and preparations) is described in this paper. After 50 minutes the six active triterpenes were separated and detected in the methanolic extract at a limit of 0.01 microg/ml.
CONCLUSIONS:
The method uses a Phenomenex Aqua 5mu C18 (200 A) column as the stationary phase, a gradient mobile phase of water (0.1% TFA), acetonitrile (0.1% TFA), and methyl tert-butyl ether (0.1% TFA), and UV detection at 206 nm. The correlation coefficients for the calibration curves and the recovery rates ranged from 0.995 to 0.999 and from 98.39% to 100.02%, respectively. The qualitative and quantitative results are discussed.

Product Name	Asiaticoside B
Price:	$158 / 20mg
CAS No.:	125265-68-1
Catalog No.:	CFN95124
Molecular Formula:	C₄₈H₇₈O₂₀
Molecular Weight:	975.13 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	Powder
Source:	The herbs of Centella asiatica (L.) Urban
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Triterpenoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.0255 mL	5.1275 mL	10.255 mL	20.5101 mL	25.6376 mL
5 mM	0.2051 mL	1.0255 mL	2.051 mL	4.102 mL	5.1275 mL
10 mM	0.1026 mL	0.5128 mL	1.0255 mL	2.051 mL	2.5638 mL
50 mM	0.0205 mL	0.1026 mL	0.2051 mL	0.4102 mL	0.5128 mL
100 mM	0.0103 mL	0.0513 mL	0.1026 mL	0.2051 mL	0.2564 mL

CFN98688	Asiatic acid	464-92-6	488.7	C₃₀H₄₈O₅
CFN96830	3-O-Coumaroylasiatic acid	143773-52-8	634.85	C₃₉H₅₄O₇
CFN99912	Asiaticoside	16830-15-2	959.12	C₄₈H₇₈O₁₉
CFN99913	Madecassoside	34540-22-2	975.13	C₄₈H₇₈O₂₀
CFN95124	Asiaticoside B	125265-68-1	975.13	C₄₈H₇₈O₂₀
CFN99914	Madecassic acid	18449-41-7	504.70	C₃₀H₄₈O₆
CFN99481	2,24-Dihydroxyursolic acid	143839-02-5	488.7	C₃₀H₄₈O₅
CFN96162	Barbinervic acid	64199-78-6	488.7	C₃₀H₄₈O₅
CFN96828	Myrianthic acid	89786-84-5	504.70	C₃₀H₄₈O₆
CFN91072	19 alpha-Hydroxyasiatic acid	70868-78-9	504.7	C₃₀H₄₈O₆