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Ebenifoline E-II
Ebenifoline E-II
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Ebenifoline E-II
Price:
CAS No.: 133740-16-6
Catalog No.: CFN92118
Molecular Formula: C48H51NO18
Molecular Weight: 929.9 g/mol
Purity: >=98%
Type of Compound: Sesquiterpenoids
Physical Desc.: Powder
Source: The stems and leaves of Euonymus laxiflorus.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Ebenifoline E-II is a natural product from Euonymus laxiflorus.
Ebenifoline E-II Description
Source: The stems and leaves of Euonymus laxiflorus.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.0754 mL 5.3769 mL 10.7538 mL 21.5077 mL 26.8846 mL
5 mM 0.2151 mL 1.0754 mL 2.1508 mL 4.3015 mL 5.3769 mL
10 mM 0.1075 mL 0.5377 mL 1.0754 mL 2.1508 mL 2.6885 mL
50 mM 0.0215 mL 0.1075 mL 0.2151 mL 0.4302 mL 0.5377 mL
100 mM 0.0108 mL 0.0538 mL 0.1075 mL 0.2151 mL 0.2688 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Nat Prod. 2003 Apr;66(4):554-7.
A novel NO-production-inhibiting triterpene and cytotoxicity of known alkaloids from Euonymus laxiflorus.[Pubmed: 12713415 ]

METHODS AND RESULTS:
A new triterpene, laxifolone A (1), four known sesquiterpene alkaloids, Ebenifoline E-II (2), carigorinine E (3), euojaponine C (4), and emarginatine E (5), and six triterpenoids, 3-hydroxyolean-12-en-22,29-gamma-lactone, 3,11-dioxo-beta-amyrene, 3beta,22alpha-dihydroxyolean-12-en-29-oic acid, 28,29-dihydroxyfriedelan-3-one, 29-hydroxy-3-oxo-D:A-friedooleanan-28-oic acid, and putranjivadione, were isolated from the stems and leaves of Euonymus laxiflorus.
CONCLUSIONS:
Structural elucidations of these compounds were established by spectral analysis. Compound 1 displayed significant nitric oxide (NO) inhibitory effect.
Angelicin

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CAS No: 523-50-2
Price: $30/20mg
Jervine

Catalog No: CFN90955
CAS No: 469-59-0
Price: $40/20mg
Salvianolic acid A

Catalog No: CFN99161
CAS No: 96574-01-5
Price: $128/20mg
Adenine

Catalog No: CFN89041
CAS No: 73-24-5
Price: $30/20mg
Calceolarioside B

Catalog No: CFN90647
CAS No: 105471-98-5
Price: $238/20mg
Neoschaftoside

Catalog No: CFN92071
CAS No: 61328-41-4
Price: $368/5mg
Asperulosidic acid

Catalog No: CFN92108
CAS No: 25368-11-0
Price: $318/20mg
Cyclo(Pro-Leu)

Catalog No: CFN90281
CAS No: 5654-86-4
Price: $238/10mg
Emodin-8-beta-D-glucoside

Catalog No: CFN99572
CAS No: 23313-21-5
Price: $118/20mg
Morusin

Catalog No: CFN97083
CAS No: 62596-29-6
Price: $128/20mg
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