Science | Nature | Cell | View More
Natural Products
Genkwanol B
Genkwanol B
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Genkwanol B
Price:
CAS No.: 142674-67-7
Catalog No.: CFN91961
Molecular Formula: C30H22O11
Molecular Weight: 558.49 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The roots of Stellera chamaejasme
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
More Impact Factor than five Cite...
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Our products had been exported to the following research institutions and universities, And still growing.
  • Kazusa DNA Research Institute (Japan)
  • Universidad Miguel Hernández (Spain)
  • Universiti Putra Malaysia(UPM) (Malaysia)
  • University of Vigo (Spain)
  • Korea Food Research Institute(K... (Korea)
  • Almansora University (Egypt)
  • Warszawski Uniwersytet Medyczny (Poland)
  • Nanjing University of Chinese M... (China)
  • National Research Council of Ca... (Canada)
  • Complutense University of Madrid (Spain)
  • University of Auckland (New Zealand)
  • More...
Package
Featured Products
More...
(-)-Gallocatechin

Catalog No: CFN99137
CAS No: 3371-27-5
Price: $128/20mg
Allicin

Catalog No: CFN90201
CAS No: 539-86-6
Price: $50/20mg
Cucurbitacin B

Catalog No: CFN99129
CAS No: 6199-67-3
Price: $70/20mg
Peiminine

Catalog No: CFN99997
CAS No: 18059-10-4
Price: $60/20mg
Astragaloside IV

Catalog No: CFN99171
CAS No: 84687-43-4
Price: $30/20mg
N-p-Coumaroyloctopamine

Catalog No: CFN97706
CAS No: 66648-45-1
Price: $218/10mg
Vincristine sulfate

Catalog No: CFN90400
CAS No: 2068-78-2
Price: $138/20mg
Prim-O-glucosylcimifugin

Catalog No: CFN98104
CAS No: 80681-45-4
Price: $40/20mg
1-Dehydro-10-gingerdione

Catalog No: CFN92374
CAS No: 136826-50-1
Price: $ / mg
Acetylshikonin

Catalog No: CFN90523
CAS No: 24502-78-1
Price: $138/20mg
Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Genkwanol B shows potent in vitro antiviral activity against respiratory syncytial virus (RSV).
Targets: RSV
In vitro:
Chin Med. 2010 Jun 21;5:23.
Antiviral biflavonoids from Radix Wikstroemiae (Liaogewanggen).[Pubmed: 20565950 ]
Radix Wikstroemiae is a common Chinese herbal medicine. The ethyl acetate fraction of the ethanolic extract of W. indica possesses potent in vitro antiviral activity against respiratory syncytial virus (RSV). This study aims to identify the antiviral components of the active fraction.
METHODS AND RESULTS:
The active fraction of the Radix Wikstroemiae extract was isolated with chromatographic methods such as silica gel, Sephadex LH-20 and semi-preparative high performance liquid chromatography (HPLC) columns. The structures of the isolated compounds were determined based on spectroscopic analyses. The in vitro antiviral activity of the compounds against RSV was tested with the cytopathic effect (CPE) reduction assay and the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) method. Four biflavonoids, namely neochamaejasmin B, Genkwanol B, Genkwanol C and stelleranol, were isolated and characterized. Genkwanol B, Genkwanol C and stelleranol, which are stereo isomers of spirobiflavonoids, showed potent anti-RSV activity whereas neochamaejasmin B did not.
CONCLUSIONS:
Neochamaejasmin B, Genkwanol B, Genkwanol C and stelleranol were isolated from Radix Wikstroemiae and the complete absolute configurations of five chiral carbons in stelleranol were substantiated for the first time. Furthermore, the anti-RSV activity of Genkwanol B, Genkwanol C and stelleranol was reported for the first time.
Genkwanol B Description
Source: The roots of Stellera chamaejasme
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
New Products More...
Quercetin-3-O-[alpha-L-rhamnose-(1...

Catalog No: CFN95506
CAS No: 1309795-36-5
Price: $318/5mg
Malabaricone C

Catalog No: CFN95475
CAS No: 63335-25-1
Price: $318/10mg
8'-O-(3-hydroxy-3-methylglutaryl)-...

Catalog No: CFN95308
CAS No: 69790-31-4
Price: $318/5mg
3'-Methoxymirificin

Catalog No: CFN95112
CAS No: 1297609-29-0
Price: $318/5mg
New compound 13

Catalog No: CFN95374
CAS No: N/A
Price: $318/5mg
Tigloylgomisin O

Catalog No: CFN95237
CAS No: 130855-74-2
Price: $368/5mg
Irigenin 3'-O-glucoside

Catalog No: CFN95578
CAS No: N/A
Price: $318/5mg
12-Acetoxy ganoderic acid D

Catalog No: CFN95535
CAS No: N/A
Price: $318/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.7905 mL 8.9527 mL 17.9054 mL 35.8108 mL 44.7636 mL
5 mM 0.3581 mL 1.7905 mL 3.5811 mL 7.1622 mL 8.9527 mL
10 mM 0.1791 mL 0.8953 mL 1.7905 mL 3.5811 mL 4.4764 mL
50 mM 0.0358 mL 0.1791 mL 0.3581 mL 0.7162 mL 0.8953 mL
100 mM 0.0179 mL 0.0895 mL 0.1791 mL 0.3581 mL 0.4476 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN95554Mahuannin B82796-37-0544.5C30H24O10
CFN95579Ephedrannin A82001-39-6556.5C30H20O11
CFN95598Epiafzelechin-(2beta-O->7,4beta->8)-ent-epicatechin135820-73-4560.5C30H24O11
CFN96491Procyanidin A241743-41-3576.5C30H24O12
CFN96495Procyanidin A1103883-03-0576.5C30H24O12
CFN95547Ephedrannin D11592431-55-4592.5C30H24O13
CFN95801Aesculitannin B114612-77-0864.8C45H36O18
CFN95451Dehydrodicatechin A36048-23-4576.5C30H24O12
CFN92679Dracoflavan C2194794-50-8522.6C33H30O6
CFN92680Dracoflavan C1194794-49-5522.6C33H30O6
Featured Products
(-)-Gallocatechin

Catalog No: CFN99137
CAS No: 3371-27-5
Price: $128/20mg
Allicin

Catalog No: CFN90201
CAS No: 539-86-6
Price: $50/20mg
Cucurbitacin B

Catalog No: CFN99129
CAS No: 6199-67-3
Price: $70/20mg
Peiminine

Catalog No: CFN99997
CAS No: 18059-10-4
Price: $60/20mg
Astragaloside IV

Catalog No: CFN99171
CAS No: 84687-43-4
Price: $30/20mg
N-p-Coumaroyloctopamine

Catalog No: CFN97706
CAS No: 66648-45-1
Price: $218/10mg
Vincristine sulfate

Catalog No: CFN90400
CAS No: 2068-78-2
Price: $138/20mg
Prim-O-glucosylcimifugin

Catalog No: CFN98104
CAS No: 80681-45-4
Price: $40/20mg
1-Dehydro-10-gingerdione

Catalog No: CFN92374
CAS No: 136826-50-1
Price: $ / mg
Acetylshikonin

Catalog No: CFN90523
CAS No: 24502-78-1
Price: $138/20mg
Tags: buy Genkwanol B | Genkwanol B supplier | purchase Genkwanol B | Genkwanol B cost | Genkwanol B manufacturer | order Genkwanol B | Genkwanol B distributor
1 Building, No. 176, CheCheng East Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Copyright© 2011-2023 | ChemFaces all rights reserved | Tel: +86-27-84237683
E-mail:manager@chemfaces.com
payment