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Indaconitine
Indaconitine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Indaconitine
Price: $218 / 20mg
CAS No.: 4491-19-4
Catalog No.: CFN99501
Molecular Formula: C34H47NO10
Molecular Weight: 629.82 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: White powder
Source: The roots of Aconitum carmichaeli Debx.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $413.4 / In-stock
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Indaconitine is a natural product from Aconitum hemsleyanum PRITZ.
Indaconitine Description
Source: The roots of Aconitum carmichaeli Debx.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.5878 mL 7.9388 mL 15.8776 mL 31.7551 mL 39.6939 mL
5 mM 0.3176 mL 1.5878 mL 3.1755 mL 6.351 mL 7.9388 mL
10 mM 0.1588 mL 0.7939 mL 1.5878 mL 3.1755 mL 3.9694 mL
50 mM 0.0318 mL 0.1588 mL 0.3176 mL 0.6351 mL 0.7939 mL
100 mM 0.0159 mL 0.0794 mL 0.1588 mL 0.3176 mL 0.3969 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chem Pharm Bull (Tokyo). 2003 May;51(5):592-4.
Hemsleyatine, a novel C19-diterpenoid alkaloid with 8-amino group from Aconitum hemsleyanum.[Pubmed: 12736463]
The new compound hemsleyatine (1) was isolated along with four known C(19)-diterpenoid alkaloids: Indaconitine (4), yunaconitine (5), chasmanine (6), and talatisamine (7) from the roots of Aconitum hemsleyanum PRITZ.
METHODS AND RESULTS:
Structures were established by spectral analysis, including tow dimeusional (2D) NMR spectroscopy and a chemical method. Hemsleyatine (1) is the first C(19)-diterpenoid alkaloid bearing the 8-amino group. In addition, the assignments of some (13)C signals for pseudaconine (3) were revised by comparison with those of hemsleyatine (1).
CFN9858313-DehydroxyindaconintineN/A613.74C34H47NO9
CFN99501Indaconitine4491-19-4629.82C34H47NO10
CFN96413Yunaconitoline259099-25-7625.69C34H43NO10
CFN90373Crassicauline A79592-91-9643.77C35H49NO10
CFN89452Carmichaenine A2065228-59-1541.67C31H43NO7
CFN89453Carmichaenine E2065228-63-7557.67C31H43NO8
CFN90689Fuziline80665-72-1453.58C24H39NO7
CFN98580Talatisamine20501-56-8421.57C24H39NO5
CFN9624310-Hydroxyneoline132362-42-6453.6C24H39NO7
CFN96267Neolinine112515-37-4423.6C23H37NO6
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