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Isocarapanaubine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Isocarapanaubine
Price:
CAS No.: 17391-09-2
Catalog No.: CFN99819
Molecular Formula: C23H28N2O6
Molecular Weight: 428.5 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Rauvolfia verticillata (Lour.) Baill.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Isocarapanaubine and reserpiline are cytotoxic constituents from the barks of Ochrosia elliptica.
Isocarapanaubine Description
Source: The herbs of Rauvolfia verticillata (Lour.) Baill.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.3337 mL 11.6686 mL 23.3372 mL 46.6744 mL 58.3431 mL
5 mM 0.4667 mL 2.3337 mL 4.6674 mL 9.3349 mL 11.6686 mL
10 mM 0.2334 mL 1.1669 mL 2.3337 mL 4.6674 mL 5.8343 mL
50 mM 0.0467 mL 0.2334 mL 0.4667 mL 0.9335 mL 1.1669 mL
100 mM 0.0233 mL 0.1167 mL 0.2334 mL 0.4667 mL 0.5834 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chem Pharm Bull (Tokyo). 2010 Aug;58(8):1085-7.
Oppositinines A and B: new vasorelaxant beta-carboline alkaloids from Neisosperma oppositifolia.[Pubmed: 20686264]

METHODS AND RESULTS:
A phytochemical study on the bark of Neisosperma oppositifolia (Apocynaceae) yielded two new beta-carboline indole alkaloids, oppositinines A (1) and B (2), together with five known alkaloids, isoreserpiline, Isocarapanaubine, vobasine, 10-methoxydihydrocorynantheol-N-oxide, and ochropposinine oxindole. Structural elucidation of 1 and 2 was performed using 2D NMR methods.
CONCLUSIONS:
Oppositinines A (1) and B (2) showed potent vasorelaxant effects on the rat aorta.
Natural Medicines,1999, 53(5):272.
Cytotoxic Alkaloids from the Barks of Ochrosia elliptica(Natural Medicine Note)[Reference: WebLink]

METHODS AND RESULTS:
Reserpiline (3) and Isocarapanaubine (4), along with ellipticine (1) and 9-methoxyellipticine (2), were isolated as the cytotoxic constituents from the barks of Ochrosia elliptica.
Danshensu

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CAS No: 22681-72-7
Price: $70/20mg
Hyperoside

Catalog No: CFN98754
CAS No: 482-36-0
Price: $50/20mg
Pratensein

Catalog No: CFN90805
CAS No: 2284-31-3
Price: $388/5mg
11-Hydroxy-sugiol

Catalog No: CFN90366
CAS No: 88664-08-8
Price: $490/5mg
Acetyleugenol

Catalog No: CFN70222
CAS No: 93-28-7
Price: $30/20mg
Delphinidin-3-sambubioside chloride

Catalog No: CFN92171
CAS No: 53158-73-9
Price: $318/5mg
Luteolin 7-rutinoside

Catalog No: CFN93556
CAS No: 20633-84-5
Price: $218/20mg
Eurycomanone

Catalog No: CFN92008
CAS No: 84633-29-4
Price: $268/20mg
Tormentic acid

Catalog No: CFN99434
CAS No: 13850-16-3
Price: $238/10mg
Kaempferide

Catalog No: CFN98782
CAS No: 491-54-3
Price: $40/20mg
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