Isothymusin | CAS:98755-25-0 | Manufacturer ChemFaces

Isothymusin

ChemFaces products have been cited in many studies from excellent and top scientific journals

Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC

How to Order

Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com

Delivery time

Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal

Citing Use of our Products

More Impact Factor than five Cite...

* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.

According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

Our products had been exported to the following research institutions and universities, And still growing.

Centralised Purchases Unit (CPU... (India)
University of Fribourg (Switzerland)
University of Padjajaran (Indonesia)
University of East Anglia (United Kingdom)

Institute of Chinese Materia Me... (China)
Worcester Polytechnic Institute (USA)
Charles University in Prague (Czech Republic)
University of Liège (Belgium)

Uniwersytet Gdański (Poland)
University of Auckland (New Zealand)
Monash University (Australia)
More...

Package

Featured Products

More...

Vicenin -3

Catalog No: CFN92032
CAS No: 59914-91-9
Price: $198/20mg

(+)-Camphor

Catalog No: CFN94889
CAS No: 464-49-3
Price: $30/20mg

Vaccarin

Catalog No: CFN90131
CAS No: 53452-16-7
Price: $30/20mg

4-Methoxyglucobrassicin

Catalog No: CFN00505
CAS No: 83327-21-3
Price: $ / mg

Notoginsenoside Fe

Catalog No: CFN93282
CAS No: 88105-29-7
Price: $100/20mg

Neoprzewaquinone A

Catalog No: CFN97087
CAS No: 630057-39-5
Price: $388/5mg

Ginkgolic acid C17:1

Catalog No: CFN98508
CAS No: 111047-30-4
Price: $218/20mg

Alismoxide

Catalog No: CFN99775
CAS No: 87701-68-6
Price: $258/20mg

Evodiamine

Catalog No: CFN99993
CAS No: 518-17-2
Price: $40/20mg

5-Hydroxy-1,7-bis(4-hydroxyphenyl)...

Catalog No: CFN96291
CAS No: 1269839-24-8
Price: $318/10mg

Description:

Isothymusin( MIC= 200 microg/mL) exhibits inhibition activity against Mycobacterium tuberculosis. It ( IC50=7.7 microg/mL ) exhibits antioxidant activity against the radical scavenging ability of DPPH.

Targets:

Antifection

In vitro:

Arch Pharm Res. 2003 Oct;26(10):816-20.

Antimycobacterial and antioxidant flavones from Limnophila geoffrayi.[Pubmed: 14609129]

The chloroform extract of the aerial part of Limnophila geoffrayi showed antimycobacterial and antioxidant activities.
METHODS AND RESULTS:
Bioassay-guided fractionation has led to the isolation of the flavones nevadensin (5,7-dihydroxy-6,8,4'-trimethoxyflavone, 1) and Isothymusin (6,7-dimethoxy-5,8,4'-trihydroxyflavone, 2). Both compounds 1 and Isothymusin exhibited inhibition activity against Mycobacterium tuberculosis, with equal MIC value of 200 microg/mL. Only Isothymusin exhibited antioxidant activity against the radical scavenging ability of DPPH, with the IC50 value of 7.7 microg/mL.
CONCLUSIONS:
The crude hexane, chloroform and methanol extracts as well as the pure compounds 1 and Isothymusin did not exhibit mutagenic activity in the Bacillus subtilis recassay.

Isothymusin Description

Source:	The herbs of Limnophila geoffrayi
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Phytochemistry. 1998 Mar;47(5):779-82.

An 8-hydroxylated external flavone and its 8-O-glucoside from Becium grandiflorum.[Pubmed: 9542170 ]

METHODS AND RESULTS:
The major vacuolar flavonoid of a greenhouse-grown plant of Becium grandiflorum has been identified as the 8-O-glucoside of Isothymusin (5,8,4'-trihydroxy-6,7-dimethoxyflavone), while the major external flavonoids in the diethyl ether surface wash of the same plant are found to be Isothymusin and cirsimaritin (5,4'-dihydroxy-7,8-dimethoxyflavone).
CONCLUSIONS:
Although Isothymusin is already known as a conversion product of thymusin (5,6,4'-trihydroxy-6,7-dimethoxyflavone) formed by means of the Wessely-Moser rearrangement, this is the first report of Isothymusin as a plant constituent, both as aglycone and glycoside. The biogenetic and chemotaxonomic implications of the occurrence of these flavonoids in B.grandiflorum are briefly discussed.

Product Name	Isothymusin
Price:
CAS No.:	98755-25-0
Catalog No.:	CFN97562
Molecular Formula:	C₁₇H₁₄O₇
Molecular Weight:	330.3 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Yellow powder
Source:	The herbs of Limnophila geoffrayi
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antioxidants Compound Library Antibacterial Compound Library Flavonoids Compound Library Antifection Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.0276 mL	15.1378 mL	30.2755 mL	60.551 mL	75.6888 mL
5 mM	0.6055 mL	3.0276 mL	6.0551 mL	12.1102 mL	15.1378 mL
10 mM	0.3028 mL	1.5138 mL	3.0276 mL	6.0551 mL	7.5689 mL
50 mM	0.0606 mL	0.3028 mL	0.6055 mL	1.211 mL	1.5138 mL
100 mM	0.0303 mL	0.1514 mL	0.3028 mL	0.6055 mL	0.7569 mL

CFN99010	Pectolinarigenin	520-12-7	314.3	C₁₇H₁₄O₆
CFN99883	Salvigenin	19103-54-9	328.3	C₁₈H₁₆O₆
CFN91034	4',5,6,7-Tetramethoxyflavone	1168-42-9	342.4	C₁₉H₁₈O₆
CFN93255	6-Demethoxytangeretin	6601-66-7	342.4	C₁₉H₁₈O₆
CFN99787	Lysionotin	152743-19-6	344.32	C₁₈H₁₆O₇
CFN93144	Gardenin B	2798-20-1	358.4	C₁₉H₁₈O₇
CFN90240	Tangeretin	481-53-8	372.37	C₂₀H₂₀O₇
CFN97137	4',5-Dihydroxyflavone	6665-67-4	254.2	C₁₅H₁₀O₄
CFN98843	Apigenin	520-36-5	270.2	C₁₅H₁₀O₅
CFN98670	Genkwanin	437-64-9	284.3	C₁₆H₁₂O₅