Rhaponticin 2''-O-gallate | CAS:94356-24-8

Rhaponticin 2''-O-gallate

ChemFaces products have been cited in many studies from excellent and top scientific journals

Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC

How to Order

Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com

Delivery time

Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal

Citing Use of our Products

More Impact Factor than five Cite...

* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.

According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $331.2 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

Featured Products

More...

Rutin

Catalog No: CFN99642
CAS No: 153-18-4
Price: $30/20mg

Dihydroevocarpine

Catalog No: CFN92786
CAS No: 15266-35-0
Price: $268/10mg

Isovitexin 2''-O-arabinoside

Catalog No: CFN90943
CAS No: 53382-71-1
Price: $318/10mg

4'-Hydroxywogonin

Catalog No: CFN98960
CAS No: 57096-02-3
Price: $268/10mg

Tormentic acid

Catalog No: CFN99434
CAS No: 13850-16-3
Price: $238/10mg

Apigenin 5-O-beta-D-glucopyranoside

Catalog No: CFN98352
CAS No: 28757-27-9
Price: $318/10mg

L-Nicotine

Catalog No: CFN99512
CAS No: 54-11-5
Price: $40/20mg

Kaempferol 3-gentiobioside

Catalog No: CFN92384
CAS No: 22149-35-5
Price: $80/20mg

Harpagoside

Catalog No: CFN98147
CAS No: 19210-12-9
Price: $70/20mg

21-O-Tigloylgymnemagenin

Catalog No: CFN90978
CAS No: 1581276-63-2
Price: $268/5mg

Description:

Rhaponticin 2''-O-gallate showed inhibitory activity of NO production in lipopolysaccharide-activated macrophages, (IC50 = 11-69 microM).

Targets:

In vitro:

Bioorg Med Chem Lett. 2000 Feb 21;10(4):323-7.

Effects of stilbene constituents from rhubarb on nitric oxide production in lipopolysaccharide-activated macrophages.[Pubmed: 10714491 ]

METHODS AND RESULTS:
Two new anthraquinone glucosides [chrysophanol 8-O-beta-D-(6'-galloyl)-glucopyranoside, aloe-emodin 1-O-beta-D-glucopyranoside] together with various known stilbenes and their glucosides, anthraquinone glucosides, and a naphthalene glucoside were isolated from the rhizome of Rheum undulatum L. Three stilbenes (rhapontigenin, piceatannol, resveratrol), a naphthalene glucoside (torachrysone 8-O-beta-D-glucopyranoside), and two stilbene glucoside gallates (Rhaponticin 2''-O-gallate, Rhaponticin 6''-O-gallate) showed inhibitory activity of NO production in lipopolysaccharide-activated macrophages, (IC50 = 11-69 microM).
CONCLUSIONS:
The oxygen functions (-OH,-OCH3) at the benzene ring were found to be essential to show the activity. Whereas, the glucoside moiety reduced the activity, while the alpha,beta-double bond did not affect the activity. Furthermore, the active stilbenes (rhapontigenin, piceatannol, resveratrol) inhibited iNOS induction.

Rhaponticin 2''-O-gallate Description

Source:	The roots of Rumex obtusifolius L.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Rhaponticin 2''-O-gallate
Price:	$288 / 5mg
CAS No.:	94356-24-8
Catalog No.:	CFN91100
Molecular Formula:	C₂₈H₂₈O₁₃
Molecular Weight:	572.51 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Powder
Source:	The roots of Rumex obtusifolius L.
Solvent:	DMSO, Pyridine, Methanol, Ethanol, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Phenols Compound Library NO Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.7467 mL	8.7335 mL	17.4669 mL	34.9339 mL	43.6674 mL
5 mM	0.3493 mL	1.7467 mL	3.4934 mL	6.9868 mL	8.7335 mL
10 mM	0.1747 mL	0.8733 mL	1.7467 mL	3.4934 mL	4.3667 mL
50 mM	0.0349 mL	0.1747 mL	0.3493 mL	0.6987 mL	0.8733 mL
100 mM	0.0175 mL	0.0873 mL	0.1747 mL	0.3493 mL	0.4367 mL

CFN98987	Dihydroresveratrol	58436-28-5	230.3	C₁₄H₁₄O₃
CFN95783	Resveratrol 12-C-beta-glucopyranoside	163527-00-2	390.4	C₂₀H₂₂O₈
CFN99021	Dihydroresveratrol 3-O-glucoside	100432-87-9	392.4	C₂₀H₂₄O₈
CFN90854	Desoxyrhapontigenin	33626-08-3	242.3	C₁₅H₁₄O₃
CFN90911	Desoxyrhaponticin	30197-14-9	404.4	C₂₁H₂₄O₈
CFN91099	Rhaponticin 6''-O-gallate	94356-23-7	572.51	C₂₈H₂₈O₁₃
CFN91100	Rhaponticin 2''-O-gallate	94356-24-8	572.51	C₂₈H₂₈O₁₃
CFN99995	2,3,5,4'-Tetrahydroxyl diphenylethylene-2-O-glucoside	82373-94-2	406.39	C₂₀H₂₂O₉
CFN98662	Pinostilbene	42438-89-1	242.3	C₁₅H₁₄O₃
CFN95285	1-(3',5'-dimethoxy)phenyl-2-[4''-O-beta-D-glucopyranosyl (6->1)-O-alpha-L-rhamnopyranosyl]phenylethane	1338076-61-1	566.6	C₂₈H₃₈O₁₂