dl-Aloesol | CAS:104871-04-7 | Manufacturer ChemFaces

dl-Aloesol

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dl-Aloesol Description

Source:	The secondary metabolites of endophytic fungus HCCB06030.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Chem Pharm Bull (Tokyo). 1991 Mar;39(3):704-8.

Metabolism of aloesin and related compounds by human intestinal bacteria: a bacterial cleavage of the C-glucosyl bond and the subsequent reduction of the acetonyl side chain.[Pubmed: 2070451]

METHODS AND RESULTS:
By anaerobic incubation with a bacterial mixture from human feces, aloesin (aloeresin B; 1) was converted to 2-acetonyl-7-hydroxy-5-methylchromone (aloesone; 3) and dl-7-hydroxy-2-(2'-hydroxypropyl)-5-methylchromone (aloesol; 4a + 4b) through a cleavage of the C-glucosyl bond, followed by reduction of the acetonyl side chain. An analogous compound, aloeresin A (2), was converted to p-coumaric acid and aloesin (1), the latter being subsequently transformed to aloesone (3) and dl-Aloesol (4a + 4b). On the other hand, 7-O-methylated derivatives (7, 5a and 5b) of aloesin and of 8-C-glucosylaloesol were not cleaved to the corresponding aglycones, suggesting the importance of a free hydroxy group adjacent to the C-glucosyl group in the molecule for the bacterial cleavage of aloesin derivatives.
CONCLUSIONS:
This is the first report on the cleavage of the C-glycosyl bond of chromone C-glucosides by intestinal bacteria.

Product Name	dl-Aloesol
Price:
CAS No.:	104871-04-7
Catalog No.:	CFN96962
Molecular Formula:	C₁₃H₁₄O₄
Molecular Weight:	234.25 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Powder
Source:	The secondary metabolites of endophytic fungus HCCB06030.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Phenols Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	4.2689 mL	21.3447 mL	42.6894 mL	85.3789 mL	106.7236 mL
5 mM	0.8538 mL	4.2689 mL	8.5379 mL	17.0758 mL	21.3447 mL
10 mM	0.4269 mL	2.1345 mL	4.2689 mL	8.5379 mL	10.6724 mL
50 mM	0.0854 mL	0.4269 mL	0.8538 mL	1.7076 mL	2.1345 mL
100 mM	0.0427 mL	0.2134 mL	0.4269 mL	0.8538 mL	1.0672 mL

CFN91098	6-Hydroxy-2-(2-phenylethyl)chromone	84294-90-6	266.29	C₁₇H₁₄O₃
CFN91097	6,7-Dimethoxy-2-phenethylchromone	84294-87-1	310.34	C₁₉H₁₈O₄
CFN96467	Undulatoside A	58108-99-9	354.31	C₁₆H₁₈O₉
CFN92909	Drynachromoside A	1507388-29-5	500.45	C₂₂H₂₈O₁₃
CFN89273	Cypellocarpin C	294856-66-9	520.53	C₂₆H₃₂O₁₁
CFN89020	Eucamalduside A	1287220-29-4	520.53	C₂₆H₃₂O₁₁
CFN92910	Monnieriside A	1401807-73-5	370.31	C₁₆H₁₈O₁₀
CFN95818	Biflorin	89701-85-9	354.3	C₁₆H₁₈O₉
CFN95819	Isobiflorin	152041-16-2	354.3	C₁₆H₁₈O₉
CFN95896	Obtusichromoneside A	2414481-20-0	442.4	C₂₀H₂₆O₁₁