Hot Products
Catalog No. | Information |
CFN98665 | Catechin 7-xyloside Catechin-7-O-xyloside has anti-cancer activity, it induces apoptosis via endoplasmic reticulum stress and mitochondrial dysfunction in human non-small cell lung carcinoma H1299 cells. |
CFN99765 | Catharanthine Catharanthine inhibits nicotinic receptor mediated diaphragm contractions with IC50 of 59.6 μM, it dilates small mesenteric arteries and decreases heart rate and cardiac contractility by inhibition of voltage-operated calcium channels on vascular smooth muscle cells and cardiomyocytes. |
CFN99007 | Caudatin Caudatin has anticancer activity, due partly to its inhibition of cell proliferation and induction of apoptosis in cancer cells through caspase activation.It inhibits carcinomic human alveolar basal epithelial cell growth and angiogenesis by targeting GSK3β/β-catenin pathway and suppressing VEGF production. Caudatin exhibits significantly inhibitory activity against HBV DNA replication with IC50 values in the range of 2.82-7.48 μM. |
CFN96052 | Caulilexin C Caulilexin C shows inhibitory activity on human Acyl CoA: cholesterol transferase I (hACATI) and on human Acyl CoA: cholesterol transferase 2 (hACAT2) at 100 mug/ml. |
CFN91135 | Caulophyllogenin Caulophyllogenin in the inhibition of pro-inflammatory cytokine secretion, including IL-12 p40, IL-6, and TNF-α, and for prevention and treatment of inflammatory diseases. |
CFN96440 | Cauloside A Cauloside A exhibits concentration- and time-dependent mitochondriotoxic activities. |
CFN98063 | Ceanothic acid Ceanothic acid derivatives show cytotoxic effect against OVCAR-3 and HeLa cancer cell lines. |
CFN99368 | Cedrelone Cedrelone exhibits antifeedant activity, it has insecticidal activity, it inhibits arval growth of P. saucia, and the molting of the milkweed bug, Oncopeltus fasciatus. Cedrelone and its derivatives exert antimicrobial activities, bromohydroxy cedrelone and Michael adduct show good antifungal activity. Cedrelone is also a very potent inducer of apoptosis, it can cause cell cycle arrest, it shows significant cytotoxicity against cancer cell lines, such as -60, SMMC-7721, A-549, MCF-7 and SW480. |
CFN97872 | Cedrin Cedrin has protective effects on PC12 cells against the neurotoxicity induced by amyloid β1-42, the protective effect is related to the inhibition of oxidative stress, improvement of mitochondrial dysfunction and suppression of apoptosis. |
CFN70197 | Cedrol Cedrol shows antifungal activity against the fungus Botrytis cinerea , it has the potential of becoming a new hair growth promoter. Cedrol has sedative effects, it induces autophagy and apoptotic cell death in A549 non-small cell lung carcinoma cells through the P13K/Akt signaling pathway, the loss of mitochondrial transmembrane potential and the generation of ROS. Cedrol is a potent competitive inhibitor of CYP2B6-mediated bupropion hydroxylase with the inhibition constant (Ki) value of 0.9, μM, it also markedly inhibited CYP3A4-mediated midazolam hydroxylation with a Ki value of 3.4 μM. |