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Natural Products
Catalog No. Information
CFN97809 Cannabisin F

Melongenamides B-D and Cannabisin F have anti-inflammatory activity, they exhibit inhibitions of nitric oxide production in lipopolysaccharide-induced RAW 264.7 macrophages with IC50 values ranging from 16.2 to 58.5 uM.
CFN94001 Cannabisin H

Reference standards.
CFN95436 Cannabisin M

CFN97198 Canniprene

Canniprene has anti-inflammatory activity, it can potently inhibit the production of inflammatory eicosanoids via the 5-lipoxygenase pathway (IC50=0.4uM) and also can affect the generation of prostaglandins via the cyclooxygenase/microsomal prostaglandin E2 synthase pathway (IC50 =10 uM).
CFN99790 Cantharidin

Cantharidin, a natural toxicant of blister beetles, is a strong inhibitor of protein phosphatases types 1 (PP1) and 2A (PP2A), and is a novel and potent multidrug resistance (MDR) reversal agent. Cantharidin has anti-tumor activity, it causes oxidative stress that provokes DNA damage and p53-dependent apoptosis, it impairs cell migration and invasion by suppressing MMP-2 and -9 through PI3K/NF-κB signaling pathways.
CFN98730 Canthin-6-one

Canthin-6-one has antimicrobial, cytotoxic, antiproliferative and proapoptotic effects, possibly by interfering with the G2/M transition; it also has antiinflammatory activity by interfering with the transcription factors NF-κB and AP-1 at transcriptional level.
CFN92010 Canthin-6-one N-oxide

Canthin-6-one N-oxide has broad spectrum antifungal, leishmanicidal and trypanocidal activities.
CFN95016 Caohuoside E

Caohuoside E is a natural product from Epimedium sagittatum.
CFN90317 Capillarisin

Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cells, it inhibits cancer cell growth of osteosarcoma cells by inducing apoptosis accompanied with G0/G1-phase cell cycle arrest and loss in mitochondrial membrane potential.Capillarisin has anti-inflammatory activity, can inhibit LPS-induced inflammation by blocking TLR4-mediated NF-κB and MAPKs activation in BV2 microglia. Capillarisin possesses promising anti-hyperalgesic and anti-allodynic effects through the inhibition of various inflammatory pain signaling.
CFN99917 Capsaicin

Capsaicin, the main pungent ingredient in 'hot' chilli peppers, is a TRPV1 agonist with EC50 of 0.29±0.05 μM in HEK293 cells, which elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system, it may used as a pain therapy by the long-lasting and inhibitory effects on persistent pain. Capsaicin has antioxidant activity , it is more effective than melatonin in suppressing the formation of lipid hydroperoxides, it also reduces anxiety-like behaviours in rats and may be an admissible drug candidate for treating endometriosis.