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Natural Products
Catalog No. Information
CFN98039 Cannabichromene

Cannabichromene is a major non-psychotropic phytocannabinoid that inhibits endocannabinoid inactivation and activates the transient receptor potential ankyrin-1 (TRPA1), it selectively reduces inflammation-induced hypermotility in vivo in a manner that is not dependent on cannabinoid receptors or TRPA1; it can raise the viability of neural stem progenitor cells (NSPCs), while inhibiting their differentiation into astroglia, possibly through up-regulation of ATP and adenosine signalling. Cannabichromene exerts anti-inflammatory actions in activated macrophages with tonic CB1 cannabinoid signalling being negatively coupled to this effect and ameliorates experimental murine colitis.
CFN91611 Cannabichromenic acid

Cannabichromenic acid is a new antibiotic active against gram-positive bacteria, including MRSA.
CFN99356 Cannabidiolic acid

Cannabidiolic acid inhibits migration of the highly invasive MDA-MB-231 human breast cancer cells, apparently through a mechanism involving inhibition of cAMP-dependent protein kinase A, coupled with an activation of the small GTPase, RhoA. Cannabidiolic acid displays significantly greater potency at inhibiting vomiting in shrews and nausea in rats, and at enhancing 5-HT(1A) receptor activation; it also selectively inhibits cyclooxygenase (COX)-2 activity with an IC(50) value around 2 microM, has 9-fold higher selectivity than COX-1 inhibition. Cannabidiolic acid and cannabidiol have inhibitory actions on the intestines of S. murinus that are not neuronallymediated or mediated via CB1 or CB2 receptors.
CFN89253 Cannabidivarin

Cannabidivarin is a potent inhibitor against gamma 2 subunit of GABAA receptors by forming a maximum of number of interactions with the docking score (-5.3), it may serve as a novel drug with definite control over childhood absence epilepsy. It is also an effective anticonvulsant in a broad range of seizure models.
CFN98287 Cannabigerol

Cannabigerol is a high affinity α2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; also binds to the CB2 receptor; it can relieve interocular pressure, which may be of benefit in the treatment of glaucoma. Cannabigerol has antimicrobial and antifungal activity, It exhibits the highest growth-inhibitory activity against the cancer cell lines. Cannabigerol is also a novel, well-tolerated appetite stimulant in pre-satiated rats.
CFN92993 Cannabinol

Cannabinol activates capsaicin-sensitive sensory nerves via a CB1 and CB2 cannabinoid receptor-independent mechanism.
CFN95278 Cannabiscitrin

CFN95287 Cannabisin A

CFN95268 Cannabisin B

Cannabisin B possesses considerable antiproliferative activity and that it may be utilised as a promising chemopreventive agent against hepatoblastoma disease. It induces autophagic cell death by inhibiting the AKT/mTOR pathway and S phase cell cycle arrest in HepG2 cell.
CFN90405 Cannabisin D

Cannabisin D is a natural product from Cannabis sativa L.