Hot Products
| Catalog No. | Information |
| CFN92097 | Gambogenic acid Gambogenic acid is an inhibitor of the FGFR signaling pathway in erlotinib-resistant non-small-cell lung cancer (NSCLC) and exhibits anti-tumor effects, it can cause aberrant autophagy to induce cell death and may suggest the potential application of Gambogenic acid as a tool or viable drug in anticancer therapies.Gambogenic acid could inhibit the proliferation of melanoma B16 cells and induce their apoptosis within certain time and concentration ranges. Its mechanism in inducing the cell apoptosis may be related to PI3K/Akt/mTOR signaling pathways. |
| CFN90172 | Gambogic acid Gambogic acid is a tissue-specific proteasome inhibitor, which has anticancer, anti-inflammatory, and anti-angiogenesis activities. Gambogic acid induces LRIG1 (leucine-rich repeat and Ig-like domain-containing-1) upregulation, which is responsible for EGFR (epidermal growth factor receptor) degradation and its downstream Akt/mTORC1 inhibition. |
| CFN98858 | gamma-Fagarine gamma-Fagarine possesses moderate levels of anti-HCV activities with IC₅₀ values being 20.4 ± 0.4 ug/ml, respectively. It has sister chromatid exchanges (SCEs)-inducing activity, it induces SCEs in human lymphocyte cultures in a dose-dependent manner. gamma-Fagarine and dictamnine are mutagenic in strain TA100 and TA98 with S9 mix, they have specific activities (His+/microgram) of about 50-70 revertant colonies in strain TA100, while in strain TA98 there are about 30-50 revertant colonies. |
| CFN98396 | gamma-Mangostin gamma-Mangostin is a dual agonist that activates both PPARδ and PPARα, is also a novel competitive antagonist for the 5-HT2A receptors in vascular smooth muscles and platelets.gamma-Mangostin has free radical scavenging activity, and antiproliferative and apoptotic activity in HepG2 cells, and exhibits antihypertensive, anti-inflammatory, analgesic effects. gamma-Mangostin could as a preventive agent of the metabolic syndrome, and could serve as a micronutrient for colon cancer prevention. |
| CFN92817 | Gamma-Tocotrienol Gamma-Tocotrienol has antioxidant activity, it as a hypocholesterolemic and antioxidant agent in rats fed atherogenic diets. Gamma-Tocotrienol is a novel blocker of the STAT3 activation pathway, it can induce the apoptosis on human gastric cancer SGC-7901 cells via mitochondria-dependent apoptosis pathway, with a potential role in future therapies for HCC and other cancers. |
| CFN96524 | Gancaonin G Gancaonin G shows antibacterial effects on the MRSA strains with MIC values of 16 microg/ml, it also shows more moderate antibacterial activity against Streptococcus mutans. |
| CFN96842 | Gancaonin I Gancaonin I exhibits anti-BsFtsZ GTPase activities; it also shows significant inhibitory activity against B. subtilis, with a MIC value of 5 uM. |
| CFN95066 | Gancaonin N Reference standards. |
| CFN90306 | Ganoderal A The oxygenated sterols( 26-oxygenosterols ganoderol A, ganoderol B, ganoderal A, and ganoderic acid Y) from G. lucidum can inhibit cholesterol biosynthesis via conversion of acetate or mevalonate as a precursor of cholesterol. |
| CFN92236 | Ganoderenic acid A Ganoderenic acid A has a potent hepatoprotective, and cytotoxic effects, it shows inhibitory activity on human aldose reductase in vitro. |
