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Natural Products
Catalog No. Information
CFN93779 Gitogenin

Gitogenin is a novel selective inhibitor of UGT1A4, it is also an inhibitor of enzyme α-glucosidase with IC50 values of 37.2±0.18 uM.Gitogenin shows moderate stimulation of release activity on growth hormone from rat pituitary cells.
CFN80115 GL3

GL3 encodes a bHLH protein that regulates trichome development in arabidopsis through interaction with GL1 and TTG1.
CFN98659 Glabranin

Glabranin has antimicrobial activity, it shows significant activities on DPPH free radical with the IC50 value of 240.20 ug/ml. Glabranin or a derivative thereof could be used to stimulate hair growth. Glabranine exerts a dose-dependent inhibitory effect in vitro on the dengue virus, it presents 70% inhibition on the dengue virus at a concentration of 25 microM.
CFN96402 Glabrene

Glabrene, Liquiritin apioside, neolicuroside, and 18β-glycyrrhetic acid are the predominant phenolic derivatives partitioning at the interface and most likely the major contributors to the notable synergistic antioxidant activity when coupled with pea protein hydrolysates (PPHs).Glabrene has estrogen-like activity, it can stimulate DNA synthesis in human endothelial cells (ECV-304; E304) and has a bi-phasic effect on proliferation of human vascular smooth muscle cells (VSMC). Glabrene and isoliquiritigenin may serve as candidates for skin-lightening agents, they exert varying degrees of inhibition on tyrosinase-dependent melanin biosynthesis.
CFN99731 Glabridin

Glabridin is a GABAA receptor positive modulator promoting fatty acid oxidation and improving learning and memory, which has antioxidative,anti-inflammatory, antimalarial, estrogen receptor agonism, anti-metastasis, anti-melanogenesis and neuroprotective effects. Glabridin may possess a therapeutic effect on metabolic disorders( such as diabetes and hyperglycemia), by modulating glucose metabolism through AMPK in skeletal muscle cells.
CFN93042 Glabrol

Glabrol is a PTP1B inhibitor, it is also a CYP1B1 inhibitor, it shows inhibition of CYP1B1 in live cell assay with the IC50 value of 15 uM. Glabrol has hypnotic effects, it induces sleep via a positive allosteric modulation of GABA(A)-BZD receptors. Glabrol possesses significant antimicrobial activity in vitro. Glabrol may have potential therapy for the treatment in obesity and type 2 diabetes patients, it shows a noncompetitive type of inhibition against diacylglycerol acyltransferase (DGAT) with an IC50 value of 8.0 microM.
CFN93135 Glabrolide

Reference standards.
CFN93041 Glabrone

Glabrone shows antiviral activity against influenza virus. It also exhibits significant PPAR-gamma ligand-binding activity.
CFN99256 Glaucin B

Glaucin B is a new bitter limonoid.
CFN90408 Glaucine

Glaucine has antitussive, antioxidative potential and antiviral activities, it may be an anti-arthritic agent, it can enhance LPS and zymosan-induced IL-10 production. Glaucine can inhibit the migration and invasion of human breast cancer cells by MMP-9 inhibitory activity, attenuating IκBα and NF-κB activities.