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Natural Products
Catalog No. Information
CFN90207 Glaucocalyxin A

Glaucocalyxin A could potentially be developed as an antiplatelet and antithrombotic agent, can inhibit platelet p-selectin secretion and integrin activation by convulxin, is a GPVI selective ligand. Glaucocalyxin A has regulation of microglia activity, can attenuate lipopolysaccharide -stimulated neuroinflammation through NF-κB and p38 MAPK signaling pathways.Glaucocalyxin A may become a potential anti-fibrotic agent in Idiopathic pulmonary fibrosis (IPF) management, it can effectively ameliorate pulmonary fibrosis through the antagonism of leukocyte infiltration and proinflammatory cytokine production.
CFN95299 Glaucoside A

Anticancer. Glaucoside A was evaluated against the HT-29 and HCT 116 human colon cancer cell lines.
CFN95300 Glaucoside C

Anticancer. Glaucoside C was evaluated against the HT-29 and HCT 116 human colon cancer cell lines.
CFN97977 Glepidotin B

Reference standards.
CFN80103 Glibenclamide

Glibenclamide is a known blocker of vascular ATP-sensitive K+ channels (KATP), used in the treatment of type 2 diabetes.Glibenclamide increases the risk for hypoglycemia by increasing insulin secretion, it plays a paradoxical protective role to protect against severe hypoglycemia-induced fatal cardiac arrhythmias; it also reduces inflammation, vasogenic edema, and caspase-3 activation after subarachnoid hemorrhage.
CFN95063 Glicoricone

Glicoricone acts as a partial estrogen antagonist. Glicoricone inhibited the monoamine oxidase with the IC50 values of 6.0 x 10(-5)-1.4 x 10(-4) M.
CFN93993 Gliotoxin

Gliotoxin, a Wnt signaling pathway inhibitor, induces growth inhibition and apoptosis in multiple colorectal cancer cell lines with mutations of the Wnt signaling pathway. Gliotoxin targets nuclear NOTCH2 in human solid tumor derived cell lines in vitro and inhibits melanoma growth in xenograft mouse model. Gliotoxin exhibits very strong anti-tuberculosis activity towards Mycobacterium tuberculosis with the the prominent MIC50 value of <0.03 uM. Gliotoxin also suppresses macrophage immune function by subverting phosphatidylinositol 3,4,5-trisphosphate homeostasis.
CFN96591 Globulol

Globulol shows antimicrobial activity against Xanthomonas vesicatoria and Bacillus subtilis, the IC50 value of 158.0 microg/ mLand 737.2 microg/ mL, respectively.
CFN00499 Glucoalyssin

CFN00497 Glucobarbarin