Hot Products
| Catalog No. | Information |
| CFN97048 | Acteoside Acteoside is a lipase inhibitor, has neuroprotective, anti-obesity,anti-inflammatory, antioxidant, anticancer, cytotoxic,antihypertensive, analgesic, and antimetastatic activities. Acteoside can promote nerve growth factor and tropomycin receptor kinase A expression, inhibit arachidonic acid release and prostaglandin E2 production induced by 0.5 microM melittin. Acteoside can protect the cells from X‑ray induced damage through enhancing the scavenging activity of ROS, decreasing the Bax/Bcl-2 ratio and downregulating the activity of procaspase-3, as well as modulating the mitogen‑activated protein kinase signaling pathways. |
| CFN98444 | Actinidic acid Actinidic acid is a triterpene phytoalexin from unripe kiwi fruit. |
| CFN94528 | Actinidine |
| CFN00012 | Actinine α-Actinine promotes metastasis in gastric cancer. |
| CFN96555 | Acuminatanol Acuminatanol is a natural product from Trichoscypha acuminata. |
| CFN98656 | Acuminatin (-)-Acuminatin exerts hepatoprotective activities, perhaps by serving as a potent antioxidant. (+)-trans-Acuminatin, and (+)-cis-acuminatin show weak activity against platelet aggregation with IC50 values of 108.5 and 90.02 uM, respectively.(-)-Acuminatin, and machilin G show dose-dependent potent inhibitory activities against PLCgamma1 in vitro with IC50 values ranging from 8.8 to 26.0 microM, the inhibition of PLCgamma1 may be an important mechanism for an antiproliferative effect on the human cancer cells, therefore, these inhibitors may be utilized as cancer chemotherapeutic and chemopreventive agents. |
| CFN95808 | Acutumine |
| CFN60066 | Adavosertib (MK-1775) Adavosertib (MK-1775, AZD1775) is a potent and selective Wee1 inhibitor with IC50 of 5.2 nM in a cell-free assay; hinders G2 DNA damage checkpoint. |
| CFN99215 | Adenanthin Adenanthin is a novel NF-κB and nucleophilic cysteines inhibitor, it has bacteriostatic, antiinflammatory, and antitumour activities. Adenanthin also has antileukemic activity through targeting peroxiredoxin I/II. Adenanthin can serve as the development of Prx I– and Prx II–targeted therapeutic agents. |
| CFN89041 | Adenine Adenine is a purine derivative and a nucleobase with a variety of roles in biochemistry. Adenine, an AMP-activated protein kinase (AMPK) activator, can accelerate the diabetic wound healing by PPAR delta and angiogenic regulation; it also can increase the inhibitory activity of human interferon against encephalomyocarditis virus. Adenine can act as an efficient radiation-protecting agent at low concentration (2 micromol) and also inhibit cytostatic properties with regard to cancer cells at higher concentration. |
