Product informatin DBs
Ganoderic acid Z
Ganoderic acid zeta , isolated from the spores, has cytotoxicity in vitro against Meth-A and LLC cell lines.[1] The binding affinities of ganoderic acid DM and Z (ΔGbind, −16.83 and−10.99 kcal mol−1) are comparable to that of current commercial drug oseltamivir (−23...
Ganoderic acid AM1
Ganoderenic acid AM1, isolated from Ganoderma lucidum, has anti-cancer properties.[1] Ganoderenic acid AM1 exhibits hepatoprotective activities against DL-galactosamine -induced cell damage in HL-7702 cells.[2] Ganoderic acid AM1 may exert their cytotoxicity by altering proteins involved in an...
Gamabufotalin
Gamabufotalin(CS-6), a bufadienolide compound from toad venom, suppresses COX-2 expression through targeting IKKβ/NF-κB signaling pathway in lung cancer cells, suggests that CS-6 exhibits potential use in the treatment of COX-2-mediated diseases such as lung cancer.[1] Gamabufotalin h...
Apigenin-7-glucuronide
Apigenin 7-O-β-D-glucuronide(AG), an active flavonoid derivative isolated from the agricultural residue of Juglans sigillata fruit husks, possesses multiple pharmacological activities, including anti-oxidant, anti-complement, and aldose reductase inhibitory activities; AG protects mice from ...
Isoforsythiaside
Isoforsythiaside, a novel phenylethanoid glycoside isolated from Forsythia suspensa, has antioxidant effect and antibacterial activity, may be as the alternative antioxidants and antibacterial agents from natural origin.[1]
Ganoderic acid LM2
Ganoderic acid LM2 exhibits potent enhancement of ConA-induced mice splenocytes proliferation in vitro.[1]
Ganoderic acid N
23-Dihydroganoderic Acid N has anticancer effects.[1]
Anemoside B4
Anemoside B4(AB4) and tetrandrine(Tet) have some reversal effect on resistant to L-OHP in Lo Vo/L-OHP cells, the molecular mechanism of the resistance reverse effect was related to down-regulation of P-gp for AB4 and down-regulation of z DHHC9 for Tet.[1] Anemoside B4, anemonin, berberine, ...
Linderalactone
Linderalactone shows significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, the IC50 is 8.48 microg/mL.[1]
1,2-Benzenediol
1,2-Dihydroxybenzene (catechol) can induce spontaneous convulsive activity in the anaesthetized mouse.[1] 1,2-Dihydroxybenzene can produce myoclonic jerks in the rat.[2] 1,2-Dihydroxybenzene-containing compounds bind to and cap cysteine residues of tau and prevent its aggregati...
