Product informatin DBs
Danshensu
Danshensu from the aqueous extract of Salvia miltiorrhiza (Danshen), has protective effects against homocysteine-induced endothelial dysfunction.[1] Shenge, made of puerarin (isolated from Pueraria lobata Ohwi., also called Kudzu) and Danshensu (isolated from the Chinese herb, Salvia miltiorrhiz...
Littorine
Littorine is not converted directly to the alkaloid, and it is suggested that it is hydrolysed in vivo to tropine and phenyl-lactic acid, the latter undergoing rearrangement to tropic acid prior to esterification with tropine.[1] There are short-term toxic effects of 1-naphthol on the digestive ...
Ganoderic acid C2
Ganoderic acid C2, isolated from the spores, has cytotoxicity in vitro against Meth-A and LLC cell lines.[1] CHCl(3) extract of the fruiting body of Ganoderma lucidum was found to show inhibitory activity on human aldose reductase in vitro, and ganoderic acid C2 and ganoderenic acid A ...
Ganoderic acid H
Ganoderic acid H( GA-H )and ganoderic acid A(GA-A ) suppress growth (cell proliferation and colony formation) and invasive behavior (adhesion, migration and invasion) of MDA-MB-231 cells; they mediate their biological effects through the inhibition of transcription factors AP-1 and NF-kappaB...
Proline
Proline accumulates in many plant species in response to environmental stress, it can act as a signaling molecule to modulate mitochondrial functions, influence cell proliferation or cell death and trigger specific gene expression, which can be essential for plant recovery from stress, the e...
Dihydroisotanshinone I
Dihydrotanshinone I and cryptotanshinone, constituents of a medicinal plant, Salvia miltiorrhiza Bunge, have antibacterial activity against a broad range of Gram positive bacteria, they have non-selectively inhibition against DNA, RNA, and protein syntheses in B. subtilis, suggest that super...
4-Hydroxybenzaldehyde
4-Hydroxybenzaldehyde, an analogue of p-hydroxybenzyl alcohol, showed an inhibitory effect on the GABA transaminase, and its inhibitory activity was higher than that of valproic acid, a known anticonvulsant ; the antioxidation and positive modulation of GABAergic neuromodulation of 4-hydroxybenza...
Ganoderic acid F
Ganoderic acid, from Ganoderma lucidum, has anti-hepatitis B activities, at 8 ug/ml inhibits replication of hepatitis B virus (HBV) in HepG2215 cells over 8 days,it also significantly protects the mice from liver injury induced by M. bovis BCG plus lipopolysaccharide (from Escherichia coli 0127:B...
Ganoderic acid S
Ganoderic acid S and Mf induce mitochondria mediated apoptosis in human cervical carcinoma HeLa cells.[1] A novel combination of triterpenoids includes at least ganoderic acid S (GAS), ganoderic acid T (GAT), ganoderic acid Me (GAMe), ganoderic acid R (GAR), and ganodermic acid S (GMAS), th...
Aristolochic acid B
Aristolochic acid II (AAII), one of the major components of the carcinogenic plant extract aristolochic acid, is known to be mutagenic and to form DNA adducts in vitro and in vivo, AAII shows more carcinogenic risk than aristolochic acid I, and this may be, at least partly, the result of its inc...
