Product informatin DBs
Palustrol
Palustrol is one of volatiles from oil or extract of M.gale, exhibits acaricidal, insecticidal, ‘pesticidal’ and/or arthropod repellent properties, may be useful sources of chemicals for the control of arthropods of medical, veterinary or agricultural importance .[1]
Sphondin
Sphondin, a furanocoumarin derivative isolated from Heracleum laciniatum, possesses an inhibitory effect on IL-1beta-induced increase in the level of COX-2 protein and PGE(2) release in A549 cells, the inhibitory mechanism, at least in part, through suppression of NF-kappaB activity, suggest...
Lithospermoside
Lithospermoside possesses strong inhibitory effects onEpstein-Barr virus early antigen (EBV-EA) activation, the potencies of which were either comparable to or stronger than that of a green tea polyphenol, it also exerts anti-tumor promoting activity in two-stage mouse skin carcinogenesis us...
Vicenin -2
Vicenin-2 (VCN-2), an active constituent of the medicinal herb Ocimum Sanctum Linn or Tulsi, it can effectively induce anti-proliferative, anti-angiogenic and pro-apoptotic effect in CaP cells (PC-3, DU-145 and LNCaP) irrespective of their androgen responsiveness or p53 status;VCN-2 in combi...
Aristolochic acid A
Aristolochic acid, a potent human carcinogen produced by Aristolochia plants, is associated with urothelial carcinoma of the upper urinary tract (UUC), exposure to aristolochic acid contributes significantly to the incidence of UUC in Taiwan and endemic (Balkan) nephropathy .[1] DNA damage by ar...
Eurycomanone
Eurycomanone has cytotoxic on HepG2 cells and Human Cervical Carcinoma Cells by inducing apoptosis through the up-regulation of p53 and Bax, and down-regulation of Bcl-2.[1,2] Eurycomanone exerts antiproliferative activity via apoptosis in Hela cells MCF-7cells .[3,4] and Eurycomanone at viable...
Hypaconitine
Hypaconitine (HA), an active and highly toxic constituent derived from Aconitum species, is widely used to treat rheumatism, the hepatic cytochrome P450-catalyzed metabolism of HA. [1] Hypaconitine, aconitine (AC) and mesaconitine(MA) are aconitum alkaloids, have highly toxic, however, thei...
Telocinobufagin
Telocinobufagin (TCB), a bufadienolide extracted from Bufo paracnemis parotoid glands, shows a reversible local anesthetic action, similar to BUPI, however, without cardiac toxicity in vitro. [1] Telocinobufagin is a novel endogenous digitalis, exhibits elevated plasma levels in patients with te...
Vanillic acid
Vanillic acid is a potent free radical scavenger, thus, it exerts protective effects in isoproterenol induced cardiotoxic rats due to its free radical scavenging, antioxidant and anti-inflammatory properties. [1] Vanillic acid has inhibitory effect on methylglyoxal-mediated glycation in apo...
24-Methylenecycloartan-3-ol
24-Methylenecycloartan-3-ol and methyl caffeate, isolated coumarins were previously obtained from M. paniculata, show weak activity against Staphylococcus aureus and Escherichia coli.[1]
