Bioactive Products
| A unique collection of 674 anticancer natural compounds for high throughput screening (HTS) and New anticancer drug research | ||
| Catalog No: | B91 | Anticancer Compound Library Screening Details |
| Size: | 1mg/well * 674 Compounds 2mg/well * 674 Compounds | |
| Cat. No. | Information |
| CFN90598 | Trachelogenin Trachelogenin has antiproliferative effect, the mechanism is related to affect the phosphorylation of key proteins such as β-Catenin, c-Myc and GSK3 in the β-Catenin signaling pathway in a concentration-dependent manner. |
| CFN97902 | Enniatin B Enniatin B has anticancer benefits, especially for the treatment of cervical cancer, it also has antiangiogenic properties, indicated by a strong inhibition of human endothelial cell migration and tube formation. Enniatin B has extensive hepatic metabolism, that reduces in vivo potential, it can decrease Monocytes' endocytosis ability and an increase of CD71. |
| CFN97914 | Altholactone Altholactone may be a potential antimicrobial agent, particularly in ciprofloxacin-refractory S. aureus and E. faecalis infections. It can inhibit the growth of various types of cancer cells through inducing apoptosis via oxidative stress, including bladder cancer, colon carcinoma cells. |
| CFN97934 | Deguelin Deguelin, acts as a chemopreventive agent by blocking multiple pathways like PI3K-Akt, IKK-NF-κB, and MAPK-mTOR-survivin-mediated apoptosis. Deguelin binding to Hsp90 leads to a decreased expression of numerous oncogenic proteins, including MEK1/2, Akt, HIF1α, COX-2, and NF-κB. Deguelin is a potent in vitro inhibitor of the mutant form of NPM1, which provides the molecular basis for its anti-leukemia activities in NPM1 mutant acute myeloid leukemia cells.Deguelin has anti-cancer activity, such as anti osteosarcoma, lung cancer; via inducing the apoptosis of cancer cells through a ROS driven Akt pathway, EPC suppression by FAK-integrin-ILK-dependent actin remodeling .Deguelin possesses antitumor effect by targeting Akt in dual axis such as EGFR and IGF1R signaling pathways and suggests that it provides an applicable therapeutic strategy for HNSCC patients. |
| CFN97946 | Phaseollin Phaseollin and neorautenol may be responsible for the anticarcinogenic actions of the plant extract, may lead to new pharmacons to be used in cancer therapy.9-Aminoacridine and other DNA intercalators function as inducers of Phaseollin and phenylalanine ammonia lyase synthesis by reacting with the DNA template.The red kidney bean phytoalexins kievitone and phaseollin possess both estrogenic and antiestrogenic activities. |
