Bioactive Products
| A unique collection of 674 anticancer natural compounds for high throughput screening (HTS) and New anticancer drug research | ||
| Catalog No: | B91 | Anticancer Compound Library Screening Details |
| Size: | 1mg/well * 674 Compounds 2mg/well * 674 Compounds | |
| Cat. No. | Information |
| CFN92801 | Inulanolide A Inulanolide A is a novel NFAT1 and MDM2 dual targeting agent and may be a clinical candidate for breast cancer therapy. Inulanolide A has potent cytotoxicity. |
| CFN92802 | 14-Deoxyandrographolide 14-Deoxyandrographolide has hepatoprotective activity, mediates activation of adenylate cyclase-cAMP signaling leading to up-regulation of cNOS, may provide a promising approach in the prevention of liver diseases during chronic alcoholism. It desensitizes hepatocytes to TNF-alpha-mediated apoptosis through the release of TNFRSF1A. |
| CFN92813 | Ginsenoside Rs3 Ginsenoside Rs3 induce apoptosis, is related to the elevations of p53 and p21WAF1 in the cells. |
| CFN92817 | Gamma-Tocotrienol Gamma-Tocotrienol has antioxidant activity, it as a hypocholesterolemic and antioxidant agent in rats fed atherogenic diets. Gamma-Tocotrienol is a novel blocker of the STAT3 activation pathway, it can induce the apoptosis on human gastric cancer SGC-7901 cells via mitochondria-dependent apoptosis pathway, with a potential role in future therapies for HCC and other cancers. |
| CFN92818 | Ginsenoside Rk2 Ginsenoside Rk1 has anti-tumor, and anti-platelet aggregation activities. Ginsenoside Rk1 can strongly inhibit permeability induced by VEGF, advance glycation end-product, thrombin, or histamine in human retinal endothelial cells, it reduces the vessel leakiness of retina in a diabetic mouse model; this anti-permeability activity of Rk1 is correlated with enhanced stability and positioning of tight junction proteins at the boundary between cells; Rk1 induces phosphorylation of myosin light chain and cortactin, which are critical regulators for the formation of the cortical actin ring structure and endothelial barrier. |
