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Bioactive Products
Anticancer Compound Library
A unique collection of 674 anticancer natural compounds for high throughput screening (HTS) and New anticancer drug research
Catalog No: B91 Anticancer Compound Library
Screening Details
Size: 1mg/well * 674 Compounds
2mg/well * 674 Compounds
Cat. No. Information
CFN97161 4',5,7-Trihydroxy-6-prenylflavone

6-Prenylapigenin(4',5,7-Trihydroxy-6-prenylflavone) shows potent inhibitory activity on melanin formation, it may be potential sources for skin whitening agents. It also shows moderate cytotoxicities against breast cancer (MDA-MB-435S) and lung adenocarcinoma (A549) cell lines.
CFN97168 Echitamine

Echitamine chloride possesses anti-tumour activity in-vitro and in-vivo.
CFN97172 Sophoridine

Sophoridine has anti-inflammatory, anti-cancer and anti-arrhythmia, and affects the immune and central nervous systems. Early and short-time applying sophoridine has neuroprotective effect min permanent middle cerebral artery occlusion (pMCAO) rat brain by down-regulating TRAF6 and up-regulating p-ERK1/2 expression, ameliorating brain infaction and edema. Sophoridine also possesses antiviral activities against Coxsackievirus B3, by regulating cytokine expression, may represent a potential therapeutic agent for viral myocarditis.
CFN97173 Sempervirine

Sempervirine can unwind circular DNA, it shows selective inhibition of in vitro synthesis of cancer DNA .
CFN97178 Moracin C

Moracin C and D, new phytoalexins from diseased mulberry, are antifungal compounds. Moracin C has potent antibacterial activity, it can inhibit FabI and fatty acid synthesis, it inhibit S. aureus FabI with IC(50) of 83.8 uM. Moracin C has anti-inflammatory effect, it can effectively reduce lipopolysaccharide (LPS) stimulated up-regulation of mRNA and protein expression of iNOS, COX-2, and serval pro-inflammatory cytokines (IL-1β, IL-6 and TNF-α).Moracin may be protective influence in tumor promotion, utilization of Moracin may open a new avenue in the treatment of tumerigenesis.