Bioactive Products
A unique collection of 35 Antileukaemic natural compound library for Antileukaemic screening | ||
Catalog No: | B29 | Antileukaemic Compound Library Screening Details |
Size: | 1mg/well * 35 Compounds 2mg/well * 35 Compounds |
Cat. No. | Information |
CFN93144 | Gardenin B Gardenin B exhibits superior antiproliferative activity against lung, breast, colon, hepatic and leukaemia cell lines as well as in keratinocytes .Gardenin B-induced cell death in human leukemia cells involves multiple caspases but is independent of the generation of reactive oxygen species. Gardenin B can strongly inhibit biochemical production of nitric oxide (IC50=10.59±0.4 ug/mL). |
CFN90889 | Sodium Dichloroacetate Sodium dichloroacetate is a drug with potential for treating patients with stroke and head injury. Sodium dichloroacetate exhibits anti-leukemic activity in B-chronic lymphocytic leukemia (B-CLL) and synergizes with the p53 activator Nutlin-3; it is cytoprotective to some colorectal cancer cells under hypoxic conditions. |
CFN90924 | Ingenol 3-Angelate Ingenol-3-angelate shows anticancer activity, and P-gp-mediated absorptive transport, dermal penetration, and vascular damage contribute to the anticancer activity of ingenol-3-angelate in vivo; it activates a broad range of PKC isoforms and induces apoptosis in acute myeloid leukemia cells by activating the PKC isoform PKCdelta. Ingenol-3-angelate suppresses HIV infection of primary CD4+ T cells through down-modulation of cell surface expression of HIV co-receptors. Ingenol-3-angelate emerges as a unique local chemotherapeutic immunostimulatory debulking agent that could be used in conjunction with immunotherapies to promote regression of metastases. |
CFN93581 | Perillyl alcohol Perillyl alcohol has potential chemopreventive, and antileukemia activities, it can suppress antigen-induced immune responses in the lung, it could be a novel preventive or therapeutic option for immunologic lung disorders such as asthma with minimal side effects. Perillyl alcohol can suppress antigen-induced immune responses in the lung, it could be a novel preventive or therapeutic option for immunologic lung disorders such as asthma with minimal side effects. |
CFN90861 | Continentalic acid Continentalic acid and kaurenoic acid are quality control markers in Aralia continentalis. Continentalic acid has anti-inflammatory, anti-cancer, and anti-bacterial activities, it shows moderate cytotoxicity against A-549 (lung), THP-1 (leukemia) and MCF-7 (breast) cell lines; it has minimum inhibitory concentrations (MICs) of approximately 8-16 microg/mL against S. aureus, including the MSSA and MRSA standard strains. |