Bioactive Products
A unique collection of 35 Antileukaemic natural compound library for Antileukaemic screening | ||
Catalog No: | B29 | Antileukaemic Compound Library Screening Details |
Size: | 1mg/well * 35 Compounds 2mg/well * 35 Compounds |
Cat. No. | Information |
CFN92259 | Ponicidin Ponicidin has anti-leukemia, immunoregulatory and anti-inflammatory functions, it also has anti-viral function especially in the upper respiratory tract infection. Ponicidin has anti-cancer activity against gastric carcinoma and lung cancer; can inhibit growth and induce apoptosis of gastric carcinoma cell line MKN28, via the signaling pathway regulated by Janus kinase 2 (JAK2) and signal transducers and activators of transcription 3 (STAT3). |
CFN92299 | 8-Shogaol 8-Shogaol can induce apoptosis in a time- and concentration-dependent manner by reactive oxygen species production and depletion of glutathione in HL-60 cells. |
CFN90537 | Embelin Embelin is an inhibitor of X-linked inhibitor of apoptosis (XIAP) with IC50 of 4.1 μM in a cell-free assay.Embelin has antitumor, antioxidant and anti-inflammatory activities. Embelin can enhance TRAIL-induced cell apoptosis through DR4 and DR5 upregulation and decrease IL-6-induced STAT3 phosphorylation, that combination of low-toxicity Embelin and TRAIL may become as a potential antileukemia strategy. |
CFN92616 | Zederone Zederone has anti-bacterial activity,it inhibits gram-positive bacteria activity. Zederone induces hepatotoxicity implicated the induction of Cyps, which leads to the formation of biological reactive metabolites and that cause the oxidative stress and liver cell injuries. |
CFN92722 | Schisanlignone A Schisanlignone A and Schisanlignone B show a significant activity against Leukaemia P-388 cell (IG(50) =10 and 40ug/mL, respectively) in vitro. |