Bioactive Products
| A unique collection of 165 natural compounds used for Hepatoprotective research and Hepatoprotective drug screening. | ||
| Catalog No: | B36 | Hepatoprotective Compound Library Screening Details |
| Size: | 1mg/well * 165 Compounds 2mg/well * 165 Compounds | |
| Cat. No. | Information |
| CFN98415 | Kaempferol 3-neohesperidoside Kaempferol 3-neohesperidoside has insulin-like properties in terms of glucose lowering, it stimulates glucose uptake in the rat soleus muscle via the PI3K and PKC pathways and, at least in part, independently of MEK pathways and the synthesis of new glucose transporters. Kaempferol 3-neohesperidoside possesses not only a significant anticancer effect against HepG2 cells, but also an effective and a dose dependent hepatoprotective and antioxidant activities due to the presence of flavonoids content. |
| CFN98509 | Decursin Decursin has antiepileptic, hepatoprotective, anti-cancer, anti-inflammatory, and anti-amnesic activities, it is a novel candidate for inhibition of VEGF-induced angiogenesis. Decursin inhibited the TGF-β1 induced NOX activation and Smad signaling, it inhibited the PKCα, MAPK and NF-κB pathways. Decursin is also a novel inhibitor of NF-kappaB activation in signaling induced by TLR ligands and cytokines. |
| CFN98459 | Palmatine Palmatine shows significant antidepressant-like, anti-hyperlipidemia, hepatoprotective, and antioxidant effects, it inhibited MAO-A, I(K) and I(CRAC) activity, and activated the AhR-CYP1A pathway. Palmatine shows the strong toxic action on T. thermophila BF5 growth, it is toxic to insects and vertebrates and inhibited the multiplication of bacteria, fungi and viruses, it is active at the alpha 2-receptor ( IC50 of 956 nM). |
| CFN98530 | Aucubin Aucubin is an iridoid glycoside with a wide range of biological activities, including pancreas-protective, chondroprotective, antispasmodic, liver-protective, anti-inflammatory, anti-microbial, antioxidant, anti-algesic as well as anti-tumor activities. Aucubin prevents neuronal death in the hippocampal CA1 region in rats with diabetic encephalopathy, it also has protective effects on H2O2-induced apoptosis in PC12 cells. Aucubin may improve obesity-induced atherosclerosis by attenuating TNF-α-induced inflammatory responses. Aucubin suppresses hepatitis B viral DNA replication in vitro. |
| CFN98486 | 3-Hydroxy-11-ursen-28,13-olide 3β-Hydroxy-urs-11-en-28,13β-olide shows a potent concentration-independent cytoprotective effect against CCl4-induced injury on human hepatoma cell line relative to silymarin as a reference standard. It exhibits weak-moderate antiproliferative activity against the A2780 human ovarian cancer cell line. |
