Bioactive Products
Cat. No. | Information |
CFN97931 | Dalbergioidin Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM. It shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyces bikiniensis that has commonly been used as an indicator organism. Dalbergioidin protects MC3T3-E1 osteoblastic cells against H2O2-induced cell damage through activation of the PI3K/AKT/SMAD1 pathway, suggests that it may be useful in bone metabolism diseases, particularly osteoporosis. Dalbergioidin also ameliorates doxorubicin-induced renal fibrosis by suppressing the TGF-β signal pathway. |
CFN90583 | Tetrahydrocurcumin Tetrahydrocurcumin can inhibit tumor angiogenesis, treat human breast cancer,and be a promising candidate for the prevention of CIPN by chemotherapeutic agents.Tetrahydrocurcumin exhibits protective effects against cisplatin-induced oxidative renal damage in rats by inhibiting cyclooxygenase-2 and caspase-3 activation; it has a protective effect over arsenic induced toxicity in rat. |
CFN93237 | Diallyl disulfide Diallyl disulfide has antitumor effect, the effect can be enhanced by miR-200b and miR-22. Diallyl disulfide induces antioxidant defense mechanism by activating Nrf2 pathway and reduces inflammatory response by inhibiting NF-κB activation. Diallyl disulfide also has protective effect against CP-induced developmental toxicity. |
CFN93091 | L-carnosine L-carnosine is an antioxidant naturally found in skeletal muscle, brain tissue, and the heart that protects cells against oxidative stress.L-carnosine plays an important role in inhibiting neuronal cell apoptosis through STAT3 signaling pathway after acute cerebral ischemia. L-carnosine may accelerate pressure ulcer healing during 4 weeks. |
CFN93196 | Troxerutin Troxerutin protects against high cholesterol-induced cognitive deficits in mice, it could be recommended as a possible candidate for the prevention and therapy of cognitive deficits in type 2 diabetes mellitus and Alzheimer's disease. Troxerutin can attenuate renal injury induced by D-galactose probably through its antioxidant and anti-inflammation properties, it also has efficacy on streptozotocin-induced rat model in the early stage of diabetic retinopathy. |