Product informatin DBs
Formononetin
Formononetin causes vascular relaxation via endothelium/NO-dependent mechanism and endothelium-independent mechanism which involves the activation of BK(Ca) and K(ATP) channels.[1] Formononetin-treated Ovx rats has an increased bone osteoprotegerin-to-receptor activator for nuclear κB liga...
Ligustilide
Ligustilide and senkyunolide A, two of the most abundant Ligusticum chuanxiong constituents, have vasorelaxation activities in contractions to various contractile agents in rat isolated aorta. [1] Ligustilide, one of the main compounds of Danggui essential oil, possesses antinociceptiv...
Beta-Sitosterol
Beta-Sitosterol a main dietary phytosterol found in plants, may have the potential for prevention and therapy for human cancer, β-sitosterol induces apoptosis in HT116 cells is associated with a decreased expression of the anti-apototic Bcl-2 protein and mRNA and a concomitant increase of th...
Ginsenoside Compound K
Ginsenoside compound K (C-K) is a metabolite of the protopanaxadiol-type saponins of Panax ginseng C.A. Meyer (Araliaceae), has long been used to treat against the development of cancer, inflammation, allergies, and diabetes; C-K acts as a unique HUVEC migration inhibitor by regulating MMP expres...
Rutin
Rutin is a natural antioxidant, all doses can diminish reactive oxygen species and high doses (10-100 microM) decrease malondialdehyde concentration; induce favorable changes in the antioxidant defense system of cultured HepG2 that prevent or delay conditions which favor cellular oxidative s...
Hydroxysafflor yellow A
Hydroxysafflor yellow A (HSYA), isolated from the dried flower of Carthamus tinctorius L. , which is extensively used in traditional Chinese medicine to treat cirrhosis, can protect against chronic carbon tetrachloride-induced liver fibrosis, might be a promising antifibrotic agent in chroni...
6-Gingerol
6-Gingerol, a natural product of ginger, has been known to possess anti-tumorigenic and pro-apoptotic activities, it stimulates apoptosis through upregulation of NAG-1 and G1 cell cycle arrest through downregulation of cyclin D1, multiple mechanisms appear to be involved in 6-gingerol action, inc...
Asperosaponin VI
Asperosaponin VI (ASA VI) is a kind of saponin in the medicinal herb Dipsacus asper Wall which has long been used as an antiosteoporosis drug, exhibits a significant induction of proliferation, differentiation and mineralization in MC3T3-E1 and primary osteoblastic cells, it may induce osteoblast...
Cyanidin-3-O-glucoside chloride
Cyanidin-3- O -glucoside, is one of the main component of mulberry anthocyanins,has protective effects from blackberry extract against peroxynitrite-induced endothelial dysfunction and vascular failure.[1] Cyanidin-3- O -glucoside exhibits strong antioxidant activities including DPPH radica...
Pachymic acid
Pachymic acid (PA) is a natural triterpenoid known to inhibit the phospholipase A2 (PLA(2)) family of arachidonic acid (AA)-producing enzymes, PA-treatment decreases bad phosphorylation, increases Bcl-2 phosphorylation, and activates caspases-9 and -3, it also decreases the expression and ac...