Product informatin DBs
Geniposide
Geniposide, a major iridoid found in fruit, is widely used in Asian countries for its anti-inflammatory, and anti-apoptotic activities, the anti-apoptotic activities is due to its modulation of and -related factors (p53, Bax, Bcl-2 and Caspase-3) in LPS-induced mouse mastitis. [1] Geniposid...
Hesperetin 7-O-glucoside
Hesperetin 7-O-glucoside and prunin are direct precursors of naringin and neohesperidin, respectively, in C. aurantium , because of the capacity of glucosyltransferase from cell-free extracts of C. aurantium tissues to glucosylate naringenin and hesperetin .[1]
Palmatine
Palmatine , a protoberberine alkaloid, is present in preparations from medicinal plants such as Coptis chinensis and Corydalis yanhusuo, palmatine activates the AhR-CYP1A pathway in HepG2 monolayer, while the potential for CYP1A induction is irrelevant in cell systems which are closer to the...
Lithospermic acid
Lithospermic acid (LSA) was originally isolated from the roots of Salvia mitiorrhiza , has antioxidant effects, is a competitive inhibitor of xanthine oxidase (XO), can directly scavenge superoxide and inhibit superoxide production in vitro, and presents hypouricemic and anti-inflamm...
Luteolin-7-O-glucoside
Luteolin-7-O-glucoside and luteolin at concentrations lower than 20 muM, significantly suppresses the productions of nitric oxide and prostaglandin E-2 (PGE(2)) in bacterial lipopolysaccharide activated-mouse macrophage RAW264.7 cells without introducing cytotoxicity; the inhibitory eff...
Amygdalin
Amygdalin induces apoptotic cell death in human DU145 and LNCaP prostate cancer cells by caspase-3 activation through down-regulation of Bcl-2 and up-regulation of Bax,suggests it may offer a valuable option for the treatment of prostate cancers.[1] Amygdalin suppresses the prostaglandin E(2) sy...
Medicarpin
Medicarpin, a legume phytoalexin, acts as an estrogen receptor (ER) agonist, can stimulate osteoblast differentiation likely via ERβ, promote achievement of peak bone mass, and is devoid of uterine estrogenicity; in addition, given its excellent oral bioavailability, it can be potential...
Alpinetin
Alpinetin is a type of novel plant flavonoid derived from Alpinia katsumadai Hayata, possesses strong anti-hepatoma effects, can suppress HepG2 cell proliferation and arrested cells in the G0/G1 phase by up-regulating the expression levels of p-MKK7, and the antitumor effect of A...
Ophiopogonin B
Ophiopogonin B (OP-B) is a bioactive component of Radix Ophiopogon Japonicus, which is often used in Chinese traditional medicine to treat pulmonary disease, it is a prospective inhibitor of PI3K/Akt and may be used as an alternative compound to treat NSCLC, it also induces apoptosis, mitotic cat...
Benzoylaconine
Benzoylaconine and aconitine can induce reproductive toxicity in BeWo Cell, the amino acid metabolism was the main metabolic pathway and responsible for the placental and fetal toxicity of them.[1]