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2-Hydroxybenzylamine
2-Hydroxybenzylamine
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 2-Hydroxybenzylamine
Price: $20 / 20mg
CAS No.: 932-30-9
Catalog No.: CFN00079
Molecular Formula: C7H9NO
Molecular Weight: 123.15 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Reseda odorata
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $4.6 / In-stock
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 2-Hydroxybenzylamine is a novel scavenger that prevents oxidative stress-induced modification of cardiac sodium channels.
Targets: Sodium Channel
In vitro:
Circulation, 2004 :17-17
2-hydroxybenzylamine: A novel scavenger that prevents oxidative stress-induced modification of cardiac sodium channels[Reference: WebLink]

METHODS AND RESULTS:
2-Hydroxybenzylamine: A novel scavenger that prevents oxidative stress-induced modification of cardiac sodium channels
2-Hydroxybenzylamine Description
Source: The herbs of Reseda odorata
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 8.1202 mL 40.6009 mL 81.2018 mL 162.4036 mL 203.0045 mL
5 mM 1.624 mL 8.1202 mL 16.2404 mL 32.4807 mL 40.6009 mL
10 mM 0.812 mL 4.0601 mL 8.1202 mL 16.2404 mL 20.3004 mL
50 mM 0.1624 mL 0.812 mL 1.624 mL 3.2481 mL 4.0601 mL
100 mM 0.0812 mL 0.406 mL 0.812 mL 1.624 mL 2.03 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chemistry, 2006,12(11): 3074–3081.
Task-Specific Ionic Liquids Bearing 2-Hydroxybenzylamine Units: Synthesis and Americium-Extraction Studies[Reference: WebLink]
The synthesis of two task-specific ionic liquids (TSILs) bearing 2-Hydroxybenzylamine entities is described.
METHODS AND RESULTS:
These compounds are based on an imidazolium substructure onto which one hydrobenzylamine-complexing moiety is grafted. We have demonstrated that, whether pure or diluted, TSIL is able to extract americium ions. Furthermore, recovery of americium from the IL phase into a receiving phase can be achieved under acidic conditions.
CONCLUSIONS:
A possible mechanism for the metal-ion partitioning is presented, in which the extraction system is driven by an ion-exchange mechanism.
International Journal of Quantum Chemistry,2010,10(12): 2179–2191.
Impact of the ionic forms on the UV–Vis spectra 2-hydroxybenzylamine. A TD-DFT study[Reference: WebLink]

METHODS AND RESULTS:
PCM-TD-DFT computations were used to examine the electronic transitions exhibited by the molecular species of 2-Hydroxybenzylamine (2-BNZ).
CONCLUSIONS:
The theoretical results thus obtained were found to accurately fit their experimental counterparts and to afford the assignation of the different experimental electronic transitions to 2-Hydroxybenzylamine tautomers present in the solution. Also, the HCTH functional was found to accurately reproduce electronic excitations in the cationic species and neutral tautomer, and the B3LYP functional to provide accurate predictions of the transitions for the anionic species and zwitterionic tautomer.
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