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2-Hydroxyplatyphyllide
2-Hydroxyplatyphyllide
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 2-Hydroxyplatyphyllide
Price:
CAS No.: 72145-19-8
Catalog No.: CFN96817
Molecular Formula: C14H14O3
Molecular Weight: 230.26 g/mol
Purity: >=98%
Type of Compound: Sesquiterpenoids
Physical Desc.: Powder
Source: The roots of Ligularia songarica.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison
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Biological Activity
Description: 2-Hydroxyplatyphyllide is a natural product from Ligularia songarica.
2-Hydroxyplatyphyllide Description
Source: The roots of Ligularia songarica.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.3429 mL 21.7146 mL 43.4292 mL 86.8583 mL 108.5729 mL
5 mM 0.8686 mL 4.3429 mL 8.6858 mL 17.3717 mL 21.7146 mL
10 mM 0.4343 mL 2.1715 mL 4.3429 mL 8.6858 mL 10.8573 mL
50 mM 0.0869 mL 0.4343 mL 0.8686 mL 1.7372 mL 2.1715 mL
100 mM 0.0434 mL 0.2171 mL 0.4343 mL 0.8686 mL 1.0857 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Zhong Yao Cai. 2014 Oct;37(10):1789-92.
Chemical constituents of Ligularia songarica.[Pubmed: 25895384]
To study the chemical constituents of Ligularia songarica.
METHODS AND RESULTS:
Isolation and purification were carried out on repeated silica gel column chromatography. The compounds structures were identified by physico-chemical properties and spectral analyses. Ten compounds were isolated and identified as benzofuranoeremophil-2-ene (1), 6-angeloyloxy-1,10-epoxy-euryopsin (2), 2-Hydroxyplatyphyllide (3), 1β-hydroxy-6,9-dien-8-oxoeremophy-11-nor-11-ketone (4), 2-isopropenyl-6-acetyl-8-methoxy-13-benzodioxin-4-one (5), 1β-hydroxy-6,9-dien-8-oxo-11-nor-11-hydroxyeremophilane (6), isopetasin (7), 6β,10α-dihydroxy-1-oxoeremophila-7 (11), 8(9)-diene-8,12-olide (8), 10α-hydroxy-1-oxo-eremophila-7 (11), 8(9)-diene-8,12-olide (9) and 6β-angeloyloxy-1β,10β-epoxy-9-oxo-furaneremophilane (10).
CONCLUSIONS:
Compounds 2-9 are obtained from this plant for the first time.
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Withaferin A

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