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2-Hydroxyxanthone
2-Hydroxyxanthone
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 2-Hydroxyxanthone
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CAS No.: 1915-98-6
Catalog No.: CFN89262
Molecular Formula: C13H8O3
Molecular Weight: 212.20 g/mol
Purity: >=98%
Type of Compound: Xanthones
Physical Desc.: Powder
Source: The twigs of Calophyllum inophyllum.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 2-Hydroxyxanthone is a natural product from Calophyllum inophyllum.
In vitro:
J Asian Nat Prod Res. 2008 Sep-Oct;10(9-10):993-7.
Cytotoxic prenylated xanthones from Calophyllum inophyllum.[Pubmed: 19003621]

METHODS AND RESULTS:
A new prenylated xanthone (1), named caloxanthone N, together with two known constituents, gerontoxanthone C (2) and 2-Hydroxyxanthone (3), was isolated from the ethanolic extract of the twigs of Calophyllum inophyllum. Their structures were completely elucidated using a combination of 1D, 2D NMR techniques (COSY, HMQC, HMBC, and ROESY) and HR-ESI-MS analyses.
CONCLUSIONS:
Compounds 1 and 2 exhibited cytotoxicity against chronic myelogenous leukemia cell line (K562) with IC50 values of 7.2 and 6.3 microg ml(- 1), respectively.
2-Hydroxyxanthone Description
Source: The twigs of Calophyllum inophyllum.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.7125 mL 23.5627 mL 47.1254 mL 94.2507 mL 117.8134 mL
5 mM 0.9425 mL 4.7125 mL 9.4251 mL 18.8501 mL 23.5627 mL
10 mM 0.4713 mL 2.3563 mL 4.7125 mL 9.4251 mL 11.7813 mL
50 mM 0.0943 mL 0.4713 mL 0.9425 mL 1.885 mL 2.3563 mL
100 mM 0.0471 mL 0.2356 mL 0.4713 mL 0.9425 mL 1.1781 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
CFN892952,5-Dihydroxy-1-methoxyxanthone173220-32-1258.22C14H10O5
CFN99684Subelliptenone G162473-22-5244.2 C13H8O5
CFN98472Mesuaxanthone A3561-81-7258.2 C14H10O5
CFN96578Tovopyrifolin C34211-53-5274.23C14H10O6
CFN962721-Hydroxy-2,3,5-trimethoxyxanthone22804-49-5302.3C16H14O6
CFN892622-Hydroxyxanthone1915-98-6212.20C13H8O3
CFN893533,4-Dihydroxy-2-methoxyxanthone6702-55-2258.22C14H10O5
CFN89359Kielcorin64280-48-4436.41C24H20O8
CFN96957Cadensin D102349-35-9466.44C25H22O9
CFN98879Euxanthone529-61-3228.2 C13H8O4
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