Science | Nature | Cell | View More
Natural Products
22-beta-Acetoxyglycyrrhizin
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 22-beta-Acetoxyglycyrrhizin
Price:
CAS No.: 938042-17-2
Catalog No.: CFN92922
Molecular Formula: C44H64O18
Molecular Weight: 880.97 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The roots of Glycyrrhiza uralensis
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Rio de Janeiro State University (Brazil)
  • Indian Institute of Science (India)
  • Auburn University (USA)
  • S.N.D.T. Women's University (India)
  • Universidad Miguel Hernández (Spain)
  • Warszawski Uniwersytet Medyczny (Poland)
  • Uniwersytet Gdański (Poland)
  • University of British Columbia (Canada)
  • University of Ioannina (Greece)
  • Monash University (Australia)
  • Universidad de La Salle (Mexico)
  • More...
Package
Featured Products
Protopine

Catalog No: CFN99399
CAS No: 130-86-9
Price: $50/20mg
Schizandrin B

Catalog No: CFN99923
CAS No: 61281-37-6
Price: $50/20mg
Cannabidiol

Catalog No: CFN99444
CAS No: 13956-29-1
Price: $40/20mg
Coptisine

Catalog No: CFN99563
CAS No: 3486-66-6
Price: $88/20mg
Zearalenone

Catalog No: CFN91172
CAS No: 17924-92-4
Price: $50/20mg
Amentoflavone

Catalog No: CFN99526
CAS No: 1617-53-4
Price: $40/20mg
Campesterol

Catalog No: CFN92204
CAS No: 474-62-4
Price: $188/10mg
Naringin

Catalog No: CFN99555
CAS No: 10236-47-2
Price: $30/20mg
(+)-Sophoranol

Catalog No: CFN92840
CAS No: 3411-37-8
Price: $ / mg
Ampelopsin

Catalog No: CFN98326
CAS No: 27200-12-0
Price: $30/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 22-beta-Acetoxyglycyrrhizin is a natural product from Glycyrrhiza uralensis.
In vitro:
J Pharm Biomed Anal. 2015 Nov 10;115:515-22.
Metabolites identification of bioactive licorice compounds in rats.[Pubmed: 26311472]
Licorice (Glycyrrhiza uralensis Fisch.) is one of the most popular herbal medicines worldwide. This study aims to identify the metabolites of seven representative bioactive licorice compounds in rats.
METHODS AND RESULTS:
These compounds include 22β-acetoxyl glycyrrhizin (22-beta-Acetoxyglycyrrhizin,1), licoflavonol (2), licoricidin (3), licoisoflavanone (4), isoglycycoumarin (5), semilicoisoflavone B (6), and 3-methoxy-9-hydroxy-pterocarpan (7). After oral administration of 250mg/kg of 1 or 40mg/kg of 2-7 to rats, a total of 16, 43 and 31 metabolites were detected in the plasma, urine and fecal samples, respectively. The metabolites were characterized by HPLC/DAD/ESI-MS(n) and LC/IT-TOF-MS analyses. Particularly, two metabolites of 1 were unambiguously identified by comparing with reference standards, and 22β-acetoxyl glycyrrhizin-6″-methyl ester (1-M2) is a new compound.
CONCLUSIONS:
Compound 1 could be readily hydrolyzed to eliminate the glucuronic acid residue. The phenolic compounds (4-7) mainly undertook phase II metabolism (glucuronidation or sulfation). Most phenolic compounds with an isoprenyl group (chain or cyclized, 2-5) could also undertake hydroxylation reaction. This is the first study on in vivo metabolism of these licorice compounds.
22-beta-Acetoxyglycyrrhizin Description
Source: The roots of Glycyrrhiza uralensis
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Gambogic acid A

Catalog No: CFN95458
CAS No: 1592842-93-7
Price: $318/5mg
Lappaol C

Catalog No: CFN95068
CAS No: 64855-00-1
Price: $333/10mg
Orientalide

Catalog No: CFN95136
CAS No: 72704-05-3
Price: $368/5mg
Dihydroconfertin

Catalog No: CFN95523
CAS No: 68832-40-6
Price: $318/5mg
cis-Aegineoside

Catalog No: CFN95295
CAS No: N/A
Price: $413/5mg
Apigenin 7-[rhamnosyl-(1->2)-galac...

Catalog No: CFN95352
CAS No: 124167-97-1
Price: $318/10mg
Betmidin

Catalog No: CFN95047
CAS No: 35589-22-1
Price: $413/5mg
6-Hydroxy-7-methoxydihydroligustil...

Catalog No: CFN95289
CAS No: 210036-09-2
Price: $318/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.1351 mL 5.6756 mL 11.3511 mL 22.7022 mL 28.3778 mL
5 mM 0.227 mL 1.1351 mL 2.2702 mL 4.5404 mL 5.6756 mL
10 mM 0.1135 mL 0.5676 mL 1.1351 mL 2.2702 mL 2.8378 mL
50 mM 0.0227 mL 0.1135 mL 0.227 mL 0.454 mL 0.5676 mL
100 mM 0.0114 mL 0.0568 mL 0.1135 mL 0.227 mL 0.2838 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protopine

Catalog No: CFN99399
CAS No: 130-86-9
Price: $50/20mg
Schizandrin B

Catalog No: CFN99923
CAS No: 61281-37-6
Price: $50/20mg
Cannabidiol

Catalog No: CFN99444
CAS No: 13956-29-1
Price: $40/20mg
Coptisine

Catalog No: CFN99563
CAS No: 3486-66-6
Price: $88/20mg
Zearalenone

Catalog No: CFN91172
CAS No: 17924-92-4
Price: $50/20mg
Amentoflavone

Catalog No: CFN99526
CAS No: 1617-53-4
Price: $40/20mg
Campesterol

Catalog No: CFN92204
CAS No: 474-62-4
Price: $188/10mg
Naringin

Catalog No: CFN99555
CAS No: 10236-47-2
Price: $30/20mg
(+)-Sophoranol

Catalog No: CFN92840
CAS No: 3411-37-8
Price: $ / mg
Ampelopsin

Catalog No: CFN98326
CAS No: 27200-12-0
Price: $30/20mg
Tags: buy 22-beta-Acetoxyglycyrrhizin | 22-beta-Acetoxyglycyrrhizin supplier | purchase 22-beta-Acetoxyglycyrrhizin | 22-beta-Acetoxyglycyrrhizin cost | 22-beta-Acetoxyglycyrrhizin manufacturer | order 22-beta-Acetoxyglycyrrhizin | 22-beta-Acetoxyglycyrrhizin distributor