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30-Oxolupeol
30-Oxolupeol
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 30-Oxolupeol
Price:
CAS No.: 64181-07-3
Catalog No.: CFN96383
Molecular Formula: C30H48O2
Molecular Weight: 440.7 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The leaves of Ilex cornuta.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Standard reference
In vitro:
Journal of Tropical & Subtropical Botany,2012,20(4):413-7.
Antibacterial Activity Components from Elephantopus tomentosus[Reference: WebLink]
Nine compounds were isolated from the ethanolic extract from the whole plant of Elephantopus tomentosus Linn.
METHODS AND RESULTS:
On the basis of spectral data,their structures were identified as epifriedelanol(1),lupeol(2),6-deoxyisojacreubin(3),butulinic acid(4),ursolic acid(5),ferulic acid(6),3-formylindole(7),pinellic acid(8) and 30-Oxolupeol(9),respectively. All compounds were obtained from Elephantopus tomentosus for the first time.
CONCLUSIONS:
Compounds 6 and 7 had inhibitory effect on Staphylococcus aureus, as well as compounds 6 and 8 exhibited inhibitory effects on Ralstonia solanacearum by paper disk diffusion method.
30-Oxolupeol Description
Source: The leaves of Ilex cornuta.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.2691 mL 11.3456 mL 22.6912 mL 45.3823 mL 56.7279 mL
5 mM 0.4538 mL 2.2691 mL 4.5382 mL 9.0765 mL 11.3456 mL
10 mM 0.2269 mL 1.1346 mL 2.2691 mL 4.5382 mL 5.6728 mL
50 mM 0.0454 mL 0.2269 mL 0.4538 mL 0.9076 mL 1.1346 mL
100 mM 0.0227 mL 0.1135 mL 0.2269 mL 0.4538 mL 0.5673 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chinese Traditional & Herbal Drugs,2012,43(3):444-7.
Chemical constituents from leaves of Ilex cornuta[Reference: WebLink]
To study the chemical constituents in the leaves of Ilex cornuta.
METHODS AND RESULTS:
The compounds were isolated and purified by silica gel,Sephadex LH-20 column chromatography,and semi-preparative HPLC,and their structures were identified by spectroscopic data and physicochemical properties. Twelve compounds were obtained from the leaves of I.cornuta and identified as(2R,3S,4S)-4-(4-hydroxy-3-methoxybenzyl)-2-(5-hydroxy-3-methoxyphenyl)-3-hydroxymethyl-tetrahydrofuran-3-ol(1),physcion(2),11-keto-α-amyrin palmitate(3),lupole(4),30-Oxolupeol(5),uvaol(6),3β-hydroxy-urs-11-en-13β(28)-olide(7),ursolic acid(8),β-sitosterol(9),daucosterol(10),pomolic acid-28-O-β-D-glucopyranoside(11),and pedunculoside(12).
CONCLUSIONS:
Compounds 1 and 2 are obtained from the plants in Ilex L.for the first time,and compounds 11 and 12 are obtained from this plant for the first time.
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Vitexin 2''-glucoside

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Trametenolic acid

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