Structure Identification: |
Chinese Traditional & Herbal Drugs,2012,43(3):444-7. | Chemical constituents from leaves of Ilex cornuta[Reference: WebLink] | To study the chemical constituents in the leaves of Ilex cornuta. METHODS AND RESULTS: The compounds were isolated and purified by silica gel,Sephadex LH-20 column chromatography,and semi-preparative HPLC,and their structures were identified by spectroscopic data and physicochemical properties. Twelve compounds were obtained from the leaves of I.cornuta and identified as(2R,3S,4S)-4-(4-hydroxy-3-methoxybenzyl)-2-(5-hydroxy-3-methoxyphenyl)-3-hydroxymethyl-tetrahydrofuran-3-ol(1),physcion(2),11-keto-α-amyrin palmitate(3),lupole(4),30-Oxolupeol(5),uvaol(6),3β-hydroxy-urs-11-en-13β(28)-olide(7),ursolic acid(8),β-sitosterol(9),daucosterol(10),pomolic acid-28-O-β-D-glucopyranoside(11),and pedunculoside(12). CONCLUSIONS: Compounds 1 and 2 are obtained from the plants in Ilex L.for the first time,and compounds 11 and 12 are obtained from this plant for the first time. |
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