Science | Nature | Cell | View More
Natural Products
4-(3,4-Dimethoxyphenyl)-3-buten-1-ol
4-(3,4-Dimethoxyphenyl)-3-buten-1-ol
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 4-(3,4-Dimethoxyphenyl)-3-buten-1-ol
Price:
CAS No.: 69768-97-4
Catalog No.: CFN97183
Molecular Formula: C12H16O3
Molecular Weight: 208.3 g/mol
Purity: >=98%
Type of Compound: Phenols
Physical Desc.: Powder
Source: The herbs of Orophea yunnanensis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • Universit?t Basel (Switzerland)
  • Vin?a Institute of Nuclear Scie... (Serbia)
  • Institute of Chinese Materia Me... (China)
  • Macau University of Science and... (China)
  • University of Lodz (Poland)
  • Univerzita Karlova v Praze (Czech Republic)
  • Wageningen University (Netherlands)
  • Heinrich-Heine-University Düss... (Germany)
  • Instituto Politécnico de Bragan?a (Portugal)
  • University of Amsterdam (Netherlands)
  • University of Wollongong (Australia)
  • More...
Package
Featured Products
Decursinol

Catalog No: CFN90496
CAS No: 23458-02-8
Price: $238/20mg
4-Hydroxybenzaldehyde

Catalog No: CFN99013
CAS No: 123-08-0
Price: $30/20mg
Afrormosine

Catalog No: CFN92347
CAS No: 550-79-8
Price: $ / mg
Secoisolariciresinol

Catalog No: CFN98363
CAS No: 29388-59-8
Price: $288/10mg
Vomifoliol

Catalog No: CFN98245
CAS No: 23526-45-6
Price: $ /
Liquiritigenin

Catalog No: CFN99156
CAS No: 578-86-9
Price: $30/20mg
Humulone

Catalog No: CFN90541
CAS No: 26472-41-3
Price: $ / mg
Linoleic acid

Catalog No: CFN93168
CAS No: 60-33-3
Price: $30/20mg
Santamarine

Catalog No: CFN98667
CAS No: 4290-13-5
Price: $ /
5-Hydroxymethylfurfural

Catalog No: CFN97149
CAS No: 67-47-0
Price: $40/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: (E)-4-(3,4-dimethoxyphenyl)but-3-en-1-ol may promote melanin synthesis via USF1 dependent fashion and could be used as a clinical therapeutic agent against hypopigmentation-associated diseases.
Targets: ERK | p38
In vitro:
PLOS ONE, 2015, 10(11):e0141988.
(E)-4-(3,4-Dimethoxyphenyl)but-3-en-1-ol Enhances Melanogenesis through Increasing Upstream Stimulating Factor-1-Mediated Tyrosinase Expression.[Reference: WebLink]

METHODS AND RESULTS:
We investigated the potential melanogenic effect of compounds from Zingiber cassumunar Roxb. Our data revealed that chloroform-soluble extract of Z. cassumunar enhanced melanin synthesis in B16F10 melanoma cells. Among the components of the chloroform extract, (E)-4-(3,4-dimethoxyphenyl)but-3-en-1-ol (4-(3,4-Dimethoxyphenyl)-3-buten-1-ol, DMPB) increased melanogenesis in both B16F10 cells and human primary melanocytes. In B16F10 cells, DMPB enhanced the activation of ERK and p38, and the level of tyrosinase. Although the level of microphthalmia-associated transcription factor was unchanged in DMPB-treated B16F10 cells, DMPB increased levels and nuclear localization of upstream stimulating factor-1 (USF1). Consistently, DMPB-mediated melanin synthesis was diminished in USF1-knockdown cells. Furthermore, DMPB induced hyperpigmentation in brown guinea pigs in vivo.
CONCLUSIONS:
Together, these data suggest that DMPB may promote melanin synthesis via USF1 dependent fashion and could be used as a clinical therapeutic agent against hypopigmentation-associated diseases.
4-(3,4-Dimethoxyphenyl)-3-buten-1-ol Description
Source: The herbs of Orophea yunnanensis
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Selaginellin

Catalog No: CFN95030
CAS No: 941269-84-7
Price: $338/5mg
Methyl lucidenate A

Catalog No: CFN95583
CAS No: 105742-79-8
Price: $318/5mg
New compound 19

Catalog No: CFN95538
CAS No: N/A
Price: $413/5mg
Ganoderic acid GS-3

Catalog No: CFN95518
CAS No: 1206781-66-9
Price: $413/5mg
Perlolyrine

Catalog No: CFN95291
CAS No: 29700-20-7
Price: $413/5mg
Maingayone B

Catalog No: CFN95483
CAS No: 1071223-57-8
Price: $318/20mg
Lanceolarin

Catalog No: CFN95166
CAS No: 15914-68-8
Price: $318/5mg
4-O-Caffeoyl-3-O-syringoylquinic a...

Catalog No: CFN95430
CAS No: 1207645-17-7
Price: $413/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 4.8008 mL 24.0038 mL 48.0077 mL 96.0154 mL 120.0192 mL
5 mM 0.9602 mL 4.8008 mL 9.6015 mL 19.2031 mL 24.0038 mL
10 mM 0.4801 mL 2.4004 mL 4.8008 mL 9.6015 mL 12.0019 mL
50 mM 0.096 mL 0.4801 mL 0.9602 mL 1.9203 mL 2.4004 mL
100 mM 0.048 mL 0.24 mL 0.4801 mL 0.9602 mL 1.2002 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Decursinol

Catalog No: CFN90496
CAS No: 23458-02-8
Price: $238/20mg
4-Hydroxybenzaldehyde

Catalog No: CFN99013
CAS No: 123-08-0
Price: $30/20mg
Afrormosine

Catalog No: CFN92347
CAS No: 550-79-8
Price: $ / mg
Secoisolariciresinol

Catalog No: CFN98363
CAS No: 29388-59-8
Price: $288/10mg
Vomifoliol

Catalog No: CFN98245
CAS No: 23526-45-6
Price: $ /
Liquiritigenin

Catalog No: CFN99156
CAS No: 578-86-9
Price: $30/20mg
Humulone

Catalog No: CFN90541
CAS No: 26472-41-3
Price: $ / mg
Linoleic acid

Catalog No: CFN93168
CAS No: 60-33-3
Price: $30/20mg
Santamarine

Catalog No: CFN98667
CAS No: 4290-13-5
Price: $ /
5-Hydroxymethylfurfural

Catalog No: CFN97149
CAS No: 67-47-0
Price: $40/20mg
Tags: buy 4-(3,4-Dimethoxyphenyl)-3-buten-1-ol | 4-(3,4-Dimethoxyphenyl)-3-buten-1-ol supplier | purchase 4-(3,4-Dimethoxyphenyl)-3-buten-1-ol | 4-(3,4-Dimethoxyphenyl)-3-buten-1-ol cost | 4-(3,4-Dimethoxyphenyl)-3-buten-1-ol manufacturer | order 4-(3,4-Dimethoxyphenyl)-3-buten-1-ol | 4-(3,4-Dimethoxyphenyl)-3-buten-1-ol distributor