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4-Allylpyrocatechol
4-Allylpyrocatechol
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 4-Allylpyrocatechol
Price: $158 / 20mg
CAS No.: 1126-61-0
Catalog No.: CFN99226
Molecular Formula: C9H10O2
Molecular Weight: 150.2 g/mol
Purity: >=98%
Type of Compound: Phenylpropanoids
Physical Desc.: Oil
Source: The leaves of Piper betle.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $36.7 / In-stock
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Product Use Citation
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 4-Allylpyrocatechol has antioxidant activity, it has protective activity against the photosensitization-induced damage to lipids and proteins of rat liver mitochondria, which attributes to its free radical and singlet oxygen scavenging properties.
In vitro:
Food Chem., 2007, 100(4):1474-80.
Inhibitory property of Piper betel extract against photosensitization-induced damages to lipids and proteins[Reference: WebLink]
The protective activity of Piper betel ethanolic extract (PE) against the photosensitization-induced damage to lipids and proteins of rat liver mitochondria has been studied.
METHODS AND RESULTS:
PE could effectively prevent lipid peroxidation, as assessed by measuring thiobarbituric acid reactive substances, lipid hydroperoxide and conjugated diene. In addition, it prevented photo-induced oxidation of proteins in a concentration-dependent manner. Furthermore, its preventive capacity against iron-mediated lipid peroxidation was also confirmed.
CONCLUSIONS:
The protective activity of PE could be attributed to its free radical and singlet oxygen scavenging properties. The activity of PE was primarily due to its phenolic constituents, which were identified as chavibetol and 4-Allylpyrocatechol.
4-Allylpyrocatechol Description
Source: The leaves of Piper betle.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 6.6578 mL 33.2889 mL 66.5779 mL 133.1558 mL 166.4447 mL
5 mM 1.3316 mL 6.6578 mL 13.3156 mL 26.6312 mL 33.2889 mL
10 mM 0.6658 mL 3.3289 mL 6.6578 mL 13.3156 mL 16.6445 mL
50 mM 0.1332 mL 0.6658 mL 1.3316 mL 2.6631 mL 3.3289 mL
100 mM 0.0666 mL 0.3329 mL 0.6658 mL 1.3316 mL 1.6644 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Zhong Yao Cai. 2014 Jan;37(1):69-71.
Chemical constituents from twigs of Piper hancei.[Pubmed: 25090708]
To investigate the chemical constituents from the twigs of Piper hancei.
METHODS AND RESULTS:
The chemical constituents were isolated and purified by means of chromatographic techniques including silica gel,Sephadex LH-20 and preparative RP-HPLC. Their structures were elucidated on the basis of physicochemical properties and spectral analysis. Eight compounds were isolated and identified as 4-Allylpyrocatechol(I), piperlonguminine(II), d-sesamin(Ill), beta-sitosterol (IV), pellitorine(V), piperolactam A(VI) and piperolactam D(VII), respectively.
CONCLUSIONS:
Compound I, III, VI and VII are isolated from Piper hancei for the first time.
CFN70479Apioline523-80-8222.2C12H14O4
CFN93217alpha-Asarone2883-98-9208.25C12H16O3
CFN98870beta-Asarone5273-86-9208.3 C12H16O3
CFN91475Gamma-Asarone5353-15-1208.3C12H16O3
CFN95655Erythro-1',2'-dihydroxyasarone146830-05-9242.3C12H18O5
CFN95656Threo-1',2'-dihydroxyasaroneN/A242.3C12H18O5
CFN98550Anethole104-46-1148.2C10H12O
CFN992264-Allylpyrocatechol1126-61-0150.2 C9H10O2
CFN99175Eugenol97-53-0164.20C10H12O2
CFN96177Methyleugenol93-15-2178.2C11H14O2
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