- ChemFaces is a professional high-purity natural products manufacturer.
- Product Intended Use
- 1. Reference standards
- 2. Pharmacological research
- 3. Inhibitors
ChemFaces products have been cited in many studies from excellent and top scientific journals
Contact Us
Order & Inquiry & Tech Support
Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method
1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / Inquiry |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
- Molecules. 2013, 18(7):7376-88
- Nutrients2020, 12(2):488
- Korean Journal of Pharmacognosy...2014...
- Plant Sci.2021, 313:111069.
- Journal of Functional Foods...2021...
- Exp Neurobiol.2018, 27(3):200-209
- Int J Mol Sci.2021, 22(8):4211.
- Int J Mol Sci.2015, 16(8):18396-411
- SBRAS2016, 12
- Sci Rep.2019, 9:12132
- Biol Pharm Bull.2017, 40(6):797-806
- Phytomedicine.2019, 58:152893
- Molecules.2018, 23(2)
- BMC Complement Altern Med....2018...
- J Biomol Struct Dyn.2022, 5;1-17.
- Plants (Basel).2021, 10(4):702.
- Kor. J. Herbol.2022, 37(5): 89-96.
- BMC Plant Biol.2022, 22(1):128.
- Ecol Evol.2022, 12(11):e9459.
- The Journal of Animal & Plant Sci...2020...
- Processes2021, 9(5),831.
- FEBS J.2022, 10.1111:febs.16676.
- Comp. & Mathematical Methods in M...2022...
- More...
Our products had been exported to the following research institutions and universities, And still growing.
- University Medical Center Mainz (Germany)
- Florida A&M University (USA)
- Imperial College London (United Kingdom)
- Universidade Federal de Santa C... (Brazil)
- Massachusetts General Hospital (USA)
- Wageningen University (Netherlands)
- University of Cincinnati (USA)
- Kazusa DNA Research Institute (Japan)
- Georgia Institute of Technology (USA)
- St. Jude Children Research Hosp... (USA)
- Biotech R&D Institute (USA)
- More...
- Int J Cosmet Sci.2022, doi:10.1111/ics.12827.
- Int Immunopharmacol.2019, 71:361-371
- Oxid Med Cell Longev.2021, 2021:4883398.
- Antioxidants (Basel).2019, 8(8):E307
- Front Plant Sci.2018, 9:1424
- J Sep Sci.2020, 201901140
- Sci Rep.2018, 8:9267
- Anal Biochem.2019, 569:10-15
- National University of Pharmacy2022, 1:73-76
- Molecules.2022, 27(22):7887.
Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
|
| Description: |
5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone (ED 50 =4.5 ug/ml ) shows cytotoxicity against L1210 cell and has inhibiting effects on ATPase from the cell. |
| Targets: |
ATPase |
5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone Description
| Source: |
The roots of Scutellaria baicalensis Georgi |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
2.7755 mL |
13.8773 mL |
27.7546 mL |
55.5093 mL |
69.3866 mL |
| 5 mM |
0.5551 mL |
2.7755 mL |
5.5509 mL |
11.1019 mL |
13.8773 mL |
| 10 mM |
0.2775 mL |
1.3877 mL |
2.7755 mL |
5.5509 mL |
6.9387 mL |
| 50 mM |
0.0555 mL |
0.2775 mL |
0.5551 mL |
1.1102 mL |
1.3877 mL |
| 100 mM |
0.0278 mL |
0.1388 mL |
0.2775 mL |
0.5551 mL |
0.6939 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
| Structure Identification: |
| Archives of Pharmacal Research,1987, 10 (4) :260-261. | | Beziehung zwischen dem UV-Absorptionsmuster einiger Flavone und ihrer gegen L1210-Zellen cytotoxischen Aktivität[Reference: WebLink] |
METHODS AND RESULTS:
The UV-pattern of several flavones, their cytotoxicities against L1210 cell and their Inhibiting effects on ATPase from the cell seem to be correlated. 5,2′-Dihydroxy-6,7,8,6′-tetramethoxyflavone (ED50=2.3 ug/ml) and 5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone (ED50=4.5 ug/ml), the most active flavones studied, have shown a narrow range of the absorbance ratio, Log εII/Log εI=1.073～1.109. They have inhibited the ATPase-activity to the greatest extent.
CONCLUSIONS:
These findings suggest that a certain angle between the flavone rings B and C plays an important role for the inhibition of the enzyme activity and thus the cytotoxicity. |
|
Tags: buy 5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone | 5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone supplier | purchase 5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone | 5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone cost | 5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone manufacturer | order 5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone | 5,2',6'-Trihydroxy-6,7,8-trimethoxyflavone distributor
