5-O-Methylgenistein | CAS:4569-98-6 | Manufacturer ChemFaces

5-O-Methylgenistein

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Description:

5-O-Methylgenistein may show free radical scavenging activity, it also may have hepatoprotective property on the model of toxic hepatitis induced by carbon tetrachloride damage.

In vivo:

Eksp Klin Farmakol. 2014;77(2):26-30.

Hepatoprotective properties of isoflavonoids from roots of Maackia amurensis on experimental carbon tetrachloride-induced hepatic damage.[Pubmed: 24791337]

Hepatoprotective properties of ethanol extract from the roots of Maackia amurensis Ruper et Maxim have been studied on the model of toxic hepatitis induced by carbon tetrachloride damage.
METHODS AND RESULTS:
It is established that the extract contains daidzein, 7-O-gentobiosides of isoflavonoids genistein, formononetin, pseudobabtige-nin, and 5-O-Methylgenistein, and 3-O-gentobiosides of pterocarpans (6aR, 11aR)-maakiain and (6aR, 11aR)-medicarpin. The administration of extract facilitates the restoration of antioxidant protection enzymes activity and reduced glutathione level, decreases the formation of toxic peroxidation products, produces normalizing impact on liver phospholipid pattern, and improves the erythrocyte tolerance to hemolytic agents.
CONCLUSIONS:
The action of isoflavonoids from Maackia amurensis in restoration of metabolic pathways of the liver and removal of toxic stress was more effective as compared to that of the reference hepatoprotector legalon.

5-O-Methylgenistein Description

Source:	The roots of Maackia amurensis Ruper et Maxim.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Phytochemistry Letters, 2009, 2(4):148-151.

Stilbene glucosides from the bulbs of Iris tingitana.[Reference: WebLink]

METHODS AND RESULTS:
Two new dimeric stilbene glucosides, tingitanol A (1) and tingitanol B (2) together with trans-resveratrol 3-O-glucopyranoside (3) in addition to three known isoflavones, 5-O-Methylgenistein (4), 5-O-Methylgenistein 7-O-β-d-glucopyranoside (5) and betavulgarin (6) have been isolated for the first time from the fresh bulbs of Iris tingitana Boiss. & Reut.
CONCLUSIONS:
Their structures were established on the basis of the spectral data and direct comparison with values from previously identified analogues. Additionally, the isolated compounds (1–6) were evaluated for the free radical scavenging activity.

Product Name	5-O-Methylgenistein
Price:
CAS No.:	4569-98-6
Catalog No.:	CFN89437
Molecular Formula:	C₁₆H₁₂O₅
Molecular Weight:	284.26 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Powder
Source:	The roots of Maackia amurensis Ruper et Maxim.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antioxidants Compound Library Hepatoprotective Compound Library Flavonoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.5179 mL	17.5895 mL	35.1791 mL	70.3581 mL	87.9477 mL
5 mM	0.7036 mL	3.5179 mL	7.0358 mL	14.0716 mL	17.5895 mL
10 mM	0.3518 mL	1.759 mL	3.5179 mL	7.0358 mL	8.7948 mL
50 mM	0.0704 mL	0.3518 mL	0.7036 mL	1.4072 mL	1.759 mL
100 mM	0.0352 mL	0.1759 mL	0.3518 mL	0.7036 mL	0.8795 mL

CFN93022	5-Methyl-7-methoxyisoflavone	82517-12-2	266.29	C₁₇H₁₄O₃
CFN95385	Violanone	52250-38-1	316.3	C₁₇H₁₆O₆
CFN95387	3'-O-Methylviolanone	56973-42-3	330.3	C₁₈H₁₈O₆
CFN90686	Dihydrodaidzein	17238-05-0	256.26	C₁₅H₁₂O₄
CFN98774	Daidzein	486-66-8	254.2	C₁₅H₁₀O₄
CFN99962	Formononetin	485-72-3	268.27	C₁₆H₁₂O₄
CFN95024	Isoformononetin	486-63-5	268.3	C₁₆H₁₂O₄
CFN90873	Daidzein dimethyl ether	1157-39-7	282.3	C₁₇H₁₄O₄
CFN98681	Genistein	446-72-0	270.2	C₁₅H₁₀O₅
CFN89437	5-O-Methylgenistein	4569-98-6	284.26	C₁₆H₁₂O₅