7-Hydroxy-3-(4-hydroxybenzyl)chroman | CAS:1180504-64-6

7-Hydroxy-3-(4-hydroxybenzyl)chroman

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Product Name	7-Hydroxy-3-(4-hydroxybenzyl)chroman
Price:	$338 / 5mg
CAS No.:	1180504-64-6
Catalog No.:	CFN92671
Molecular Formula:	C₁₆H₁₆O₃
Molecular Weight:	256.3 g/mol
Purity:	>=98%
Type of Compound:	Flavonoids
Physical Desc.:	Powder
Source:	The herbs of Dracaena cochinchinensis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / $236.6 / In-stock
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

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Description:

7-Hydroxy-3-(4-hydroxybenzyl)chroman shows moderate inhibitory activity against a chymotrypsin-like activity of the proteasome.

In vitro:

Biol Pharm Bull. 2005 Sep;28(9):1798-800.

7-hydroxy-3-(4-hydroxybenzyl)chroman and broussonin b: neurotrophic compounds, isolated from Anemarrhena asphodeloides BUNGE, function as proteasome inhibitors.[Pubmed: 16141565]

METHODS AND RESULTS:
The extract of Anemarrhenae Rhizoma (rhizomes of Anemarrhena asphodeloides BUNGE) showed neurotrophic activity toward rat pheochromocytoma (PC-12) cells. Bioassay-guided purification afforded four compounds, 2,6,4'-trihydroxy-4-methoxybenzophenone (1), 7-Hydroxy-3-(4-hydroxybenzyl)chroman (2), broussonin B (3), and cis-hinokiresinol (4).
CONCLUSIONS:
Compounds 1-3 induced neurite outgrowth in PC-12 cells at concentration of 50 microg/ml, while 4 was less active. In addition, compounds 2-4 showed moderate inhibitory activities against a chymotrypsin-like activity of the proteasome.

7-Hydroxy-3-(4-hydroxybenzyl)chroman Description

Source:	The herbs of Dracaena cochinchinensis
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Inhibitors Compound Library Flavonoids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	3.9017 mL	19.5084 mL	39.0168 mL	78.0336 mL	97.5419 mL
5 mM	0.7803 mL	3.9017 mL	7.8034 mL	15.6067 mL	19.5084 mL
10 mM	0.3902 mL	1.9508 mL	3.9017 mL	7.8034 mL	9.7542 mL
50 mM	0.078 mL	0.3902 mL	0.7803 mL	1.5607 mL	1.9508 mL
100 mM	0.039 mL	0.1951 mL	0.3902 mL	0.7803 mL	0.9754 mL

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CFN92769	4-O-Methylepisappanol	112529-37-0	318.3	C₁₇H₁₈O₆
CFN92771	3'-Deoxy-4-O-methylepisappanol	1052714-12-1	302.3	C₁₇H₁₈O₅
CFN92832	Sappanol	111254-19-4	304.3	C₁₆H₁₆O₆
CFN99068	4-O-Methylsappanol	104778-16-7	318.3	C₁₇H₁₈O₆
CFN92770	3'-Deoxy-4-O-methylsappanol	112408-68-1	302.3	C₁₇H₁₈O₅
CFN92964	Sappanone B	104778-15-6	302.28	C₁₆H₁₄O₆
CFN98844	2-Hydroxy-7-O-methylscillascillin	52096-50-1	342.3	C₁₈H₁₄O₇
CFN98869	Scillascillin	52706-07-7	312.3	C₁₇H₁₂O₆
CFN99209	7,3',4'-Trihydroxy-3-benzyl-2H-chromene	1111897-60-9	270.3	C₁₆H₁₄O₄