7-Oxo-ganoderic acid Z | CAS:929248-72-6

7-Oxo-ganoderic acid Z

ChemFaces products have been cited in many studies from excellent and top scientific journals

Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC

How to Order

Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com

Delivery time

Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal

Citing Use of our Products

More Impact Factor than five Cite...

* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.

According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.

Size /Price /Stock	10 mM * 1 mL in DMSO / Inquiry
Other Packaging	*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap

Our products had been exported to the following research institutions and universities, And still growing.

University of Hawaii Cancer Center (USA)
Medical University of South Car... (USA)
University of Otago (New Zealand)
Universidad de Antioquia (Colombia)

St. Jude Children Research Hosp... (USA)
University of Wisconsin-Madison (USA)
Wageningen University (Netherlands)
National Cancer Institute (USA)

Heinrich-Heine-University Düss... (Germany)
Mahatma Gandhi University (India)
Kyung Hee University (Korea)
More...

Package

Featured Products

More...

Camelliaside A

Catalog No: CFN93559
CAS No: 135095-52-2
Price: $318/20mg

Trans-Ferulic acid

Catalog No: CFN92394
CAS No: 537-98-4
Price: $30/20mg

Astin C

Catalog No: CFN95189
CAS No: 148057-23-2
Price: $318/10mg

Campesterol

Catalog No: CFN92204
CAS No: 474-62-4
Price: $188/10mg

Puerarin

Catalog No: CFN99169
CAS No: 3681-99-0
Price: $30/20mg

Vicenin -1

Catalog No: CFN92030
CAS No: 35927-38-9
Price: $268/20mg

4-O-Feruloylquinic acid

Catalog No: CFN92392
CAS No: 2613-86-7
Price: $368/10mg

Angoroside C

Catalog No: CFN98149
CAS No: 115909-22-3
Price: $98/20mg

3,3',4',5,6,7,8-heptamethoxyflavone

Catalog No: CFN95021
CAS No: 1178-24-1
Price: $268/10mg

Cauloside A

Catalog No: CFN96440
CAS No: 17184-21-3
Price: $318/10mg

Description:

7-Oxo-ganoderic acid Z shows strong inhibitory effects against α-glucosidase, it also exhibits inhibitory activities against the HMG-CoA reductase and acyl CoA acyltransferase. 7-Oxo-ganoderic acid Z can reduce cell growth in three human carcinoma cells (Caco-2, HepG2, and HeLa cells) dose dependently with LC50s from 20.87 to 84.36 uM.

Targets:

HMG-CoA Reductase

In vitro:

Phytochemistry. 2018 May;149:103-115.

Lanostane triterpenes from the mushroom Ganoderma resinaceum and their inhibitory activities against α-glucosidase.[Pubmed: 29490285 ]

Eighteen previously undescribed lanostane triterpenes and thirty known analogues were obtained from the fruiting bodies of Ganoderma resinaceum. Resinacein C was isolated from a natural source for the first time.
METHODS AND RESULTS:
The structures of all the above compounds were elucidated by extensive spectroscopic analysis and comparisons of their spectroscopic data with those reported in the literature. Furthermore, in an in vitro assay, Resinacein C, ganoderic acid Y, lucialdehyde C, 7-Oxo-ganoderic acid Z3, 7-Oxo-ganoderic acid Z, and lucidadiol showed strong inhibitory effects against α-glucosidase compared with the positive control drug acarbose.
CONCLUSIONS:
The structure-activity relationships of ganoderma triterpenes on α-glucosidase inhibition showed that the C-24/C-25 double bond is necessary for α-glucosidase inhibitory activity. Moreover, the carboxylic acid group at C-26 and the hydroxy group at C-15 play important roles in enhancing inhibitory effects of these triterpenes.

7-Oxo-ganoderic acid Z Description

Source:	The fruit body of Ganoderma lucidum
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	7-Oxo-ganoderic acid Z
Price:
CAS No.:	929248-72-6
Catalog No.:	CFN92998
Molecular Formula:	C₃₀H₄₆O₄
Molecular Weight:	470.68 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	Powder
Source:	The fruit body of Ganoderma lucidum
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Triterpenoids Compound Library HMG-CoA Reductase Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	2.1246 mL	10.6229 mL	21.2459 mL	42.4917 mL	53.1146 mL
5 mM	0.4249 mL	2.1246 mL	4.2492 mL	8.4983 mL	10.6229 mL
10 mM	0.2125 mL	1.0623 mL	2.1246 mL	4.2492 mL	5.3115 mL
50 mM	0.0425 mL	0.2125 mL	0.4249 mL	0.8498 mL	1.0623 mL
100 mM	0.0212 mL	0.1062 mL	0.2125 mL	0.4249 mL	0.5311 mL

CFN90298	Ganoderic acid TN	112430-64-5	512.73	C₃₂H₄₈O₅
CFN92996	Ganoderic acid X	86377-53-9	512.72	C₃₂H₄₈O₅
CFN92997	Ganoderic acid Jb	112430-68-9	470.68	C₃₀H₄₆O₄
CFN92235	Ganoderic acid TR	862893-75-2	468.7	C₃₀H₄₄O₄
CFN92237	Ganoderic acid T-Q	112430-66-7	510.7	C₃₂H₄₆O₅
CFN99083	Coccinic acid	107783-45-9	454.7	C₃₀H₄₆O₃
CFN92727	Anwuweizonic acid	117020-59-4	454.7	C₃₀H₄₆O₃
CFN92998	7-Oxo-ganoderic acid Z	929248-72-6	470.68	C₃₀H₄₆O₄
CFN99815	Ganoderic acid DM	173075-45-1	468.7	C₃₀H₄₄O₄
CFN95593	11-Keto-ganoderic acid DM	N/A	482.7	C₃₀H₄₂O₅