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Aricine
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Product Name Aricine
Price:
CAS No.: 482-91-7
Catalog No.: CFN98760
Molecular Formula: C22H26N2O4
Molecular Weight: 382.5 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The herbs of Rauvolfia vomitoria Afzel.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Aricine has cytotoxicity.
In vitro:
Phytotherapy Research,1988,2(1):25-29.
In vitro cytotoxicity testing of natural products using guinea‐pig ear keratinocytes[Reference: WebLink]

METHODS AND RESULTS:
A simple test is described in which the inhibition of uptake of [G-3H]thymidine into guinea-pig ear keratinocytes in vitro, has been used as an assessment for cytotoxicity of a series of alkaloids. The alkaloids tested include emetine, colchicine, coronaridine, ajmaline, Aricine, vincristine, leurosine, quinamine, 3-epiquinamine, quinine, quinidinone, cichonidine, berberine and atropine.
Aricine Description
Source: The herbs of Rauvolfia vomitoria Afzel.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.6144 mL 13.0719 mL 26.1438 mL 52.2876 mL 65.3595 mL
5 mM 0.5229 mL 2.6144 mL 5.2288 mL 10.4575 mL 13.0719 mL
10 mM 0.2614 mL 1.3072 mL 2.6144 mL 5.2288 mL 6.5359 mL
50 mM 0.0523 mL 0.2614 mL 0.5229 mL 1.0458 mL 1.3072 mL
100 mM 0.0261 mL 0.1307 mL 0.2614 mL 0.5229 mL 0.6536 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Natural Product Communications, 2012, 7(11):1441-1444.
A new monoterpenoid oxindole alkaloid from Hamelia patens micropropagated plantlets.[Reference: WebLink]

METHODS AND RESULTS:
Chemical studies on Hamelia patens (Rubiaceae) micropropagated plantlets allowed production of a new monoterpenoid oxindole alkaloid, named (-)-hameline (7), together with eight known alkaloids, tetrahydroalstonine (1), Aricine (2), pteropodine (3), isopteropodine (4), uncarine F (5), speciophylline (6), palmirine (8), and rumberine (9). The structure of the new alkaloid was assigned on the basis of 1D and 2D NMR spectroscopy, mass spectrometry, and molecular modeling.
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Withaferin A

Catalog No: CFN91895
CAS No: 5119-48-2
Price: $298/20mg
8-Prenylkaempferol

Catalog No: CFN92346
CAS No: 28610-31-3
Price: $ / mg
Isocorynoxeine

Catalog No: CFN98155
CAS No: 51014-29-0
Price: $128/20mg
Licoricesaponin G2

Catalog No: CFN92915
CAS No: 118441-84-2
Price: $368/20mg
Madecassoside

Catalog No: CFN99913
CAS No: 34540-22-2
Price: $40/20mg
Isosilybin A

Catalog No: CFN91070
CAS No: 142796-21-2
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Price: $118/20mg
1-O-Acetylbritannilactone

Catalog No: CFN89438
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Price: $218/20mg
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