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Bourjotinolone A
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Bourjotinolone A
Price:
CAS No.: 6985-35-9
Catalog No.: CFN97185
Molecular Formula: C30H48O4
Molecular Weight: 472.7 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The barks of Phellodendron chinense Schneid.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
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Biological Activity
Description: Standard reference
Targets: NO
In vitro:
Chinese Traditional & Herbal Drugs,2014 ,45 (6):755-759
Chemical constituents from Toona ciliata var.henryi and their anti-inflammatory activities[Reference: WebLink]
To study the chemical constituents from Toona ciliata var.henryi and their bioactivities.
METHODS AND RESULTS:
Column chromatography on silica gel,RP-C18,and Sephadex LH-20 columns was used to separate and purify the chemical constituents.The structures were elucidated by physicochemical properties and spectroscopic analyses.These compounds were isolated and evaluated for their inhibitory effects on lipopolysaccharide-induced nitric oxide production in RAW264.7 cells. Fifteen compounds were isolated from the stem barks of T.ciliata var.henryi and identified as odoratone(1),toonaciliatin F(2),toonaciliatin G(3),toonaciliatin J(4),hispidone(5),Bourjotinolone A(6),3-episapeline A(7),piscidinol A(8),aglaiodiol(9),toonaciliatin M(10),2α,19-dihydroxy-9-epi-ent-pimara-7,15-diene(11),cleomiscosin B(12),cleomiscosin C(13),β-sitosterol(14),and β-daucositerol(15).The IC50 values of compounds 4 and 10 were(11.0 ± 0.7) and(28.8 ± 2.7) μmol/L.
CONCLUSIONS:
All the compounds are isolated from this plant for the first time.Compounds 11—13 are yielded from the plants of Toona Roem.for the first time.Compounds 4 and 10 show the moderate inhibitory activities.
Bourjotinolone A Description
Source: The barks of Phellodendron chinense Schneid.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

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doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1155 mL 10.5775 mL 21.1551 mL 42.3101 mL 52.8877 mL
5 mM 0.4231 mL 2.1155 mL 4.231 mL 8.462 mL 10.5775 mL
10 mM 0.2116 mL 1.0578 mL 2.1155 mL 4.231 mL 5.2888 mL
50 mM 0.0423 mL 0.2116 mL 0.4231 mL 0.8462 mL 1.0578 mL
100 mM 0.0212 mL 0.1058 mL 0.2116 mL 0.4231 mL 0.5289 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Molecules. 2013 Mar 1;18(3):2840-50.
New limonoids and a dihydrobenzofuran norlignan from the roots of Toona sinensis.[Pubmed: 23455673]

METHODS AND RESULTS:
Two new limonoids, toonins A (1) and B (2), and one new dihydrobenzofuran norlignan, toonin C (3), were isolated from the roots of Toona sinensis together with the ten known compounds 4-methoxy-6-(2',4'-dihydroxy-6'-methylphenyl)-pyran-2-one (4), Bourjotinolone A (5), proceranone (6), matairesinol (7), 4-hydroxy-3-methoxybenzene-ethanol (8), syringic acid (9), isoscopoletin (10), lyoniresinol (11), aloeemodin (12), and β-sitosterol (13).
CONCLUSIONS:
Their structures were elucidated on the basis of one- and two-dimensional spectroscopic analysis. Isolation of compounds 4, 6-13 from this plant is reported here for the first time.
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