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Calystegine C2
Calystegine C2
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Calystegine C2
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CAS No.: 190957-44-9
Catalog No.: CFN00160
Molecular Formula: C7H13NO5
Molecular Weight: 191.18 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Oil
Source: The leaves of Duboisia leichhardtii.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF
Similar structural: Comparison (Web)  (SDF)
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Related Screening Libraries
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Biological Activity
Description: Calystegine C2, the 2-epimer of calystegine C1, exhibits an inhibitory activity against beta-glucosidase and beta-galactosidase.
Calystegine C2 Description
Source: The leaves of Duboisia leichhardtii.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

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After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
More...

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 5.2307 mL 26.1534 mL 52.3067 mL 104.6135 mL 130.7668 mL
5 mM 1.0461 mL 5.2307 mL 10.4613 mL 20.9227 mL 26.1534 mL
10 mM 0.5231 mL 2.6153 mL 5.2307 mL 10.4613 mL 13.0767 mL
50 mM 0.1046 mL 0.5231 mL 1.0461 mL 2.0923 mL 2.6153 mL
100 mM 0.0523 mL 0.2615 mL 0.5231 mL 1.0461 mL 1.3077 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Kinase Assay:
Phytochemistry,1997,45( 2): 425-9.
Calystegine alkaloides from Duboisia leichhardtii.[Reference: WebLink]

METHODS AND RESULTS:
Pentahydroxy-nor-tropane alkaloids, calystegines C1 and C2, were isolated from the leaves of greenhouse-cultivated Duboisia leichhardtii, together with calystegines B1, B2 and B4. Calystegine C1 is a potent inhibitor of beta-glucosidase and beta-galactosidase, whereas Calystegine C2 exhibited no significant inhibitory activity against these enzymes.
CONCLUSIONS:
Only Calystegine C2, the 2-epimer of calystegine C1, among calystegines isolated to date exhibited an inhibitory activity against all alpha-mannosidases tested.
CFN001593,6-Ditigloyloxynortropane359723-70-9307.39C17H25NO4
CFN00160Calystegine C2190957-44-9191.18C7H13NO5
CFN00161Calystegine B2127414-85-1175.18C7H13NO4
CFN00162Calystegine B3178231-95-3175.18C7H13NO4
CFN001528-Azabicyclo[3.2.1]octane-2,3-diolN/A143.18C7H13NO2
CFN00154Baogongteng C107259-50-7143.18C7H13NO2
CFN00155Baogongteng A74239-84-2185.22C9H15NO3
CFN001562,6-Tropanediol65356-02-7157.21C8H15NO2
CFN00157Erycibelline107633-95-4143.18C7H13NO2
CFN001588-Azabicyclo[3.2.1]octane-3,6-diolN/A143.18C7H13NO2
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